{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:45:54Z","timestamp":1773009954529,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U21A20523"],"award-info":[{"award-number":["U21A20523"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To analyze the influence of RV dysfunction evaluated by Free\u2010angle M\u2010mode (FAM) TAPSE <jats:italic>Z<\/jats:italic>\u2010score on retrograde ductus arteriosus flow (RDAF) in fetuses with Ebstein anomaly (EA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of 30 EA and 60 normal fetuses were enrolled. The EA group was divided into two groups: with RDAF (EA\u2010RDAF group) and without RDAF (EA\u2010NRDAF group). FAM was used to measure TAPSE of EA and normal fetuses, and <jats:italic>Z<\/jats:italic>\u2010scores were calculated. The differences of FAM\u2010TAPSE <jats:italic>Z<\/jats:italic>\u2010score, gestational week (GW), maternal age (MA), and mitral valve\u2010tricuspid valve distance (MTD) between three groups were compared. The correlation and binary logistic regression between FAM\u2010TAPSE <jats:italic>Z<\/jats:italic>\u2010score, GW, MA, MTD, and RDAF were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>FAM\u2010TAPSE <jats:italic>Z<\/jats:italic>\u2010score was significantly lower in EA\u2010RDAF group compared to other groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). FAM\u2010TAPSE <jats:italic>Z<\/jats:italic>\u2010score, GW, and MA were negatively correlated with RDAF (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), but no correlation was found between TR, MDT, and RDAF (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Multivariate logistic regression showed that FAM\u2010TAPSE <jats:italic>Z<\/jats:italic>\u2010score was an independent influencing factor for RDAF (OR\u2009=\u20090.102, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>RV dysfunction is an independent factor leading to RDAF in EA fetus, which provides a feasible theoretical basis for further study on improvement of RV function through intrauterine treatment to delay and prevent the RDAF, to avoid death cycle and improve live\u2010birth rate.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23695","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T09:03:02Z","timestamp":1713949382000},"page":"717-722","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Study on the correlation between retrograde ductus arteriosus flow and right ventricular function evaluated by <i>Z<\/i>\u2010score of tricuspid annular plane systolic excursion in fetuses with Ebstein anomaly"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9447-4597","authenticated-orcid":false,"given":"Xianfeng","family":"Guo","sequence":"first","affiliation":[{"name":"Maternal\u2010Fetal Medicine Center in Fetal Heart Disease, Beijing Anzhen Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bowen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital Zhejiang University College of Medicine  Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihua","family":"He","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Center in Fetal Heart Disease, Beijing Anzhen Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2003.05.003"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.015839"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2016.03.008"},{"issue":"11","key":"e_1_2_10_5_1","first-page":"951","article-title":"Z\u2010score analysis of tricuspid annular plane systolic excursion in normal fetuses with fetal echocardiography","volume":"24","author":"Guo XF","year":"2015","journal-title":"Chin J Ultrasonogr"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-013-0680-x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.09.022"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016684"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.11.013"},{"issue":"2","key":"e_1_2_10_10_1","first-page":"121","article-title":"Application of annular plane systolic excursion z\u2010score in evaluation of heart systolic function of fetus with heart failure","volume":"26","author":"Guo XF","year":"2017","journal-title":"Chin J Ultrasonogr"},{"issue":"1","key":"e_1_2_10_11_1","first-page":"15","article-title":"Effect of prenatal transplacental digoxin therapy on fetal heart failure: a non\u2010randomized controlled trial","volume":"8","author":"Zhou KY","year":"2013","journal-title":"Chin J Evid Based 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