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Initial attempt with endoscopic dilation was not successful. The patient underwent Heineke\u2013Mikulicz pyloroplasty. Full oral feeding was achieved by Day 7 postoperatively. At 6\u2010month follow\u2010up, the patient reported relief of symptoms, normal feeding habits and substantial weight gain. HPS should be considered in the differential diagnosis of recurrent vomiting, regardless of age. A comprehensive diagnostic work\u2010up, including ultrasonography, endoscopy, and CT, is recommended to confirm the diagnosis.<\/jats:p>","DOI":"10.1002\/jcu.23777","type":"journal-article","created":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T08:29:50Z","timestamp":1722673790000},"page":"1456-1462","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unusual late\u2010onset hypertrophic pyloric stenosis in an adolescent girl with down syndrome: Case report and review of the literature"],"prefix":"10.1002","volume":"52","author":[{"given":"Annalisa","family":"Chiodi","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery Federico II University Hospital  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3256-7576","authenticated-orcid":false,"given":"Maria","family":"Escolino","sequence":"additional","affiliation":[{"name":"Division of 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