{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:59:18Z","timestamp":1772992758363,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,1]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n This study aims to compare the elastographic properties of the ovaries of patients with poor ovarian response (POR) with healthy controls by using real\u2010time ultrasound tissue elastography and to investigate the predictive value of ovarian strain ratio (OSR) in the diagnosis of POR.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n A cross\u2010sectional study was conducted among infertility patients. OSR measurements of 46 women diagnosed with POR and 41 healthy controls with male infertility were performed by real\u2010time ultrasound tissue elastography. Ovarian volume, OSR, antral follicle count (AFC), age, body mass index (BMI), anti\u2010mullerian hormone (AMH), follicle stimulating hormone (FSH), and estradiol (E2) values, were compared between the groups. A receiver operating characteristic curve was used to compare the sensitivity and specificity of OSR, AFC, AMH, FSH, and E2 for POR diagnosis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Patients with POR were significantly older, had a lower duration of infertility, lower AMH, higher FSH, higher E2, lower AFC and ovarian volume (\n p<\/jats:italic>\n \u2009<\u20090.01,\n p<\/jats:italic>\n \u2009=\u20090.02,\n p<\/jats:italic>\n \u2009<\u20090.01,\n p<\/jats:italic>\n \u2009<\u20090.01,\n p<\/jats:italic>\n \u2009<\u20090.01,\n p<\/jats:italic>\n \u2009<\u20090.01,\n p<\/jats:italic>\n \u2009<\u20090.01, respectively). The mean OSR of both ovaries was similar between the groups. For the diagnosis of POR, the sensitivity and specificity for AMH were 97.5% and 100%, for AFC were 86.7% and 97.6%; for FSH were 66.7% and 80.5%, for E2 were 53.3% and 90.2%, respectively.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The significant independent predictors of the POR were AMH, AFC, and FSH, with no additional significant contribution from OSR. However, considering the relationship between POR and ovarian fibrosis, it is recommended to investigate this issue in more comprehensive studies.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jcu.23827","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T06:31:59Z","timestamp":1726641119000},"page":"90-96","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Can ultrasound elastography be useful in the diagnosis of poor ovarian response?"],"prefix":"10.1002","volume":"53","author":[{"given":"Ebru Sahin","family":"Gulec","sequence":"first","affiliation":[{"name":"Clinic of In vitro fertilization Health Sciences University Izmir Tepecik Education and Research Hospital Konak Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esra Bahar","family":"Gur","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinic of Obstetrics and Gynecology Izmir Katip Celebi University Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Secil Karaca","family":"Kurtulmus","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinic of Obstetrics and Gynecology Izmir Katip Celebi University Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilgesu Cetinel","family":"Kaygun","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynecology Ayd\u0131n Gynecology and Pediatrics Hospital Aydin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1719-4257","authenticated-orcid":false,"given":"Esin","family":"Kasap","sequence":"additional","affiliation":[{"name":"Clinic of In vitro fertilization Health Sciences University Izmir Tepecik Education and Research Hospital Konak Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Demir","sequence":"additional","affiliation":[{"name":"Clinic of In vitro fertilization Health Sciences University Izmir Tepecik Education and Research Hospital Konak Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,18]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem408"},{"key":"e_1_2_13_3_1","volume-title":"Assisted Reproductive Technology National Summary Report","author":"Centers for Disease Control and Prevention","year":"2016"},{"issue":"1","key":"e_1_2_13_4_1","first-page":"89","article-title":"Prognosis and cost\u2010effectiveness of IVF in poor responders according to the Bologna criteria","volume":"70","author":"Busnelli A","year":"2018","journal-title":"Minerva Ginecol"},{"key":"e_1_2_13_5_1","first-page":"1128","article-title":"Comparison of different ovarian hyperstimulation protocols efficacy in poor ovarian responders according to the Bologna criteria","volume":"7","author":"Hu L","year":"2014","journal-title":"Int 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