{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:28:00Z","timestamp":1792801680511,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Pubertal gynecomastia (PG) is defined as benign proliferation of male breast tissue. Ultrasonography is frequently used for follow\u2010up of symptomatic gynecomastia. Shear wave elastography (SWE) is an auxiliary tool for the diagnosis of breast disorders. Our aim is to evaluate SWE properties of breast tissue in PG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fifty consecutive adolescents, aged 10\u201318 with a diagnosis of gynecomastia were prospectively included in the study. Following clinical and laboratory evaluation, participants underwent B\u2010mode ultrasound and classified as nodular, dendritic, and diffuse pattern. SWE and hormonal values of all groups were recorded. Then, statistical analysis was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Briefly, 92 breasts (43 left and 49 right; 42 bilateral and 8 unilateral) were included in the analyses. There were no significant differences in clinical parameters including age, BMI\u2010SDS, estradiol (E2), testosterone (T), and E\n                      <jats:sub>2<\/jats:sub>\n                      \/T levels within groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Breast volume and SWE levels were significantly different in all groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). SWE values were significantly lower for those of dendritic pattern than in nodular pattern (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). ROC analysis revealed that for the best the cut\u2010off value of 13.7\u2009kPa, area under the curve value was 0.922 with 84% sensitivity and 87% specificity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SWE values were significantly lower in patients with dendritic gynecomastia than those with nodular gynecomastia. Knowledge of the SWE values for the initial diagnosis and follow\u2010up values could help avoid unnecessary interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcu.23831","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T11:27:18Z","timestamp":1727090838000},"page":"227-233","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessing adolescent gynecomastia: The role of shear wave ultrasound elastography"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4210-7554","authenticated-orcid":false,"given":"Ay\u015fe Eda","family":"Parlak","sequence":"first","affiliation":[{"name":"Department of Radiology University of Health Sciences Antalya Training and Research Hospital  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0983-762X","authenticated-orcid":false,"given":"Ozlem Vardar","family":"Gok","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Health Sciences Antalya Training and Research Hospital  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1947-8341","authenticated-orcid":false,"given":"Iclal Erdem","family":"Toslak","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Health Sciences Antalya Training and Research Hospital  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3776-9975","authenticated-orcid":false,"given":"Riza Taner","family":"Baran","sequence":"additional","affiliation":[{"name":"Department of Pediatrics; Endocrinology Division University of Health Sciences Antalya Training and Research Hospital  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3550-1425","authenticated-orcid":false,"given":"Mesut","family":"Parlak","sequence":"additional","affiliation":[{"name":"Department of Pediatrics; Endocrinology Division Akdeniz University, Akdeniz \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi Dumlup\u0131nar  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2002.15.5.553"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328306a07c"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2007.03.010"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1347166"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199302183280708"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4274\/jcrpe.galenos.2019.2019.0027"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328305e415"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-015-3402-0"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.333125137"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(01)00483-1"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2017.06.009"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.18650"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-011-2340-y"},{"issue":"1082","key":"e_1_2_12_15_1","article-title":"Shear\u2010wave elastography quantitative assessment of the male breast: added value to distinguish benign and malignant palpable masses","volume":"91","author":"Cromb\u00e9 A","year":"2018","journal-title":"Br J Radiol"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-1024"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.tb02206.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-024-05934-4"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.264055116"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jus.2011.06.004"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2016.01.009"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.5505\/ktd.2021.31932"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.978311"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-023-03506-9"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.23831","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcu.23831","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.23831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:56:41Z","timestamp":1785833801000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.23831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,23]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/jcu.23831"],"URL":"https:\/\/doi.org\/10.1002\/jcu.23831","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,23]]},"assertion":[{"value":"2024-07-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}