{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:18:45Z","timestamp":1747149525958,"version":"3.40.5"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T00:00:00Z","timestamp":1731542400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Necrosis, a rare histologic alteration caused by the fine\u2010needle aspiration biopsy (FNA) of thyroid tumors, could be problematic in the clinical management of such cases due to the difficulty in making a definitive histopathologic diagnosis. The aim of this study was to define US features that may help to predict FNA\u2010induced necrosis which is more common in oncocytic tumors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This cross\u2010sectional study consists of all patients who underwent thyroid surgery in our center between January 2011 and December 2023. All nodules, which complete\/near\u2010complete necrosis reported on final histopathology, were included into study when full video record of preoperative US exam also available for re\u2010evaluation. US findings of necrotic tumors compared with control group consisting of similar histopathology without necrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 11 patients have met the inclusion criteria during study period. Of these cases, seven were papillary thyroid carcinomas and four were follicular adenomas. Among the evaluated distinctive US features, necrotic ring offers the best accuracy (88%) and area under the curve (0.91) values in detecting necrosis after FNA and most valuable when combined with lack of intranodular vascularity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the preoperative evaluation of surgical candidates, necrotic ring, refractive edge shadowing, posterior acoustic enhancement, and lack of vascular signal may predict complete\/near\u2010complete necrosis with great accuracy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23895","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T12:16:24Z","timestamp":1731586584000},"page":"477-486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sonography Could Predict Complete\/Near\u2010Complete Necrosis of Thyroid Tumors After Fine\u2010Needle Biopsy: Necrotic Ring Sign"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4939-8721","authenticated-orcid":false,"given":"Seyfettin","family":"Ilgan","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine G\u00fcven Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2670-9734","authenticated-orcid":false,"given":"Banu","family":"Bilezik\u00e7i","sequence":"additional","affiliation":[{"name":"Department of Pathology G\u00fcven Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-008-9578-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2009.03522.x"},{"issue":"2","key":"e_1_2_9_4_1","first-page":"99","article-title":"Worrisome Histologic Alterations Following Fine\u2010Needle Aspiration of the Thyroid (WHAFFT)","volume":"29","author":"LiVolsi V. 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