{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T16:26:15Z","timestamp":1755793575254,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to compare prenatal ultrasound markers and perinatal outcomes in newborns with simple and complex gastroschisis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study was performed on pregnant women with gastroschisis fetuses and their respective newborns between 2009 and 2019. Binary logistic regression was used to determine the best prenatal ultrasound markers of complex gastroschisis and adverse perinatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After delivery, 36 gastroschisis were classified as simple and 10 as complex. Newborns with complex gastroschisis had a higher prevalence of early neonatal death compared to newborns with simple gastroschisis (30.0% vs. 2.8%, <jats:italic>p<\/jats:italic>\u2009=\u20090.007). The abdominal wall defect diameter became a significant prenatal ultrasound marker of neonatal sepsis [X2: 6.31 (1), OR:0.92, CI 95% (0.85\u20130.98), <jats:italic>p<\/jats:italic>\u2009=\u20090.020]. The presence of complex gastroschisis [X2: 7.33 (1), OR: 23.25, CI 95% 1.92\u2013280.77, <jats:italic>p<\/jats:italic>\u2009=\u20090.013] was the only significant predictor of early neonatal death, and the presence of complex gastroschisis increased the risk of early neonatal death by 23.25 times. There was no significant effect of the type of gastroschisis in relation to gestational age, amniotic fluid index, intra\u2010abdominal intestinal dilation, extra\u2010abdominal intestinal dilation, and thickness of the intestine diameter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Abdominal wall defect diameter was a significant prenatal ultrasound marker of adverse perinatal outcomes in newborns with simple and complex gastroschisis. Complex gastroschisis was a significant predictor of early neonatal death.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23901","type":"journal-article","created":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T06:25:41Z","timestamp":1732343141000},"page":"496-503","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal Ultrasound Markers of Adverse Perinatal Outcomes in Newborns With Simple and Complex Gastroschisis"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2333-6159","authenticated-orcid":false,"given":"Jo\u00e3o Victor Jacomele","family":"Caldas","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Paulista School of Medicine Federal University of S\u00e3o Paulo (EPM\u2010UNIFESP)  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1655-3609","authenticated-orcid":false,"given":"Alberto Borges","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Gynecology and Obstetrics Service, M\u00e1rio Palm\u00e9rio University Hospital University of Uberaba (UNIUBE)  Uberaba Minas Gerais Brazil"},{"name":"Department of Obstetrics and Gynecology Federal University of Tri\u00e2ngulo Mineiro (UFTM)  Uberaba Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8739-4115","authenticated-orcid":false,"given":"Liliam Cristine","family":"Rolo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Paulista School of Medicine Federal University of S\u00e3o Paulo (EPM\u2010UNIFESP)  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6145-2532","authenticated-orcid":false,"given":"Edward","family":"Araujo J\u00fanior","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Paulista School of Medicine Federal University of S\u00e3o Paulo (EPM\u2010UNIFESP)  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2013.10.003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000464245"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12565"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-0017"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.20004"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20367"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4984"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000440699"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10225215"},{"issue":"7","key":"e_1_2_9_11_1","first-page":"540","article-title":"Amniotic Fluid Volume Assessment With the Four\u2010Quadrant Technique at 36\u201342\u2009weeks' Gestation","volume":"32","author":"Phelan J. 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