{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:49:30Z","timestamp":1792003770280,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Giant cell tumor of soft tissue (GCT\u2010ST) is an extremely rare phenomenon in the breast. Herein, a case involving a 75\u2010year\u2010old female with a painless lump and bloody discharge from the nipple of her left breast is reported. A diagnosis of malignant tumor was arrived at by observing the location of the tumor, interior echo, margins, vascular distribution, hardness, and microvascular density on preoperative multimodal ultrasonography. However, no evidence of malignancy was found on ultrasonography\u2010guided nuclear needle biopsy or rapid intraoperative pathological examination. Subsequently, an excisional biopsy was performed, and GCT\u2010ST coincident with high\u2010grade ductal carcinoma in\u00a0situ were confirmed using histopathology and immunohistochemistry. Accordingly, the patient underwent left\u2010sided mastectomy and sentinel lymph node biopsy. This case emphasizes the complexity of the clinical and pathological diagnosis of GCT\u2010ST in the breast and may raise the awareness of clinicians and sonographers to the advantages of multimodal ultrasound imaging in the diagnosis of GCT\u2010ST in the breast. Pathologists should consider the possibility of GCT\u2010ST when encountering a giant cell\u2010rich mass in the breast.<\/jats:p>","DOI":"10.1002\/jcu.23902","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T20:54:19Z","timestamp":1733777659000},"page":"885-892","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multimodal Ultrasound Imaging in the Diagnosis of Primary Giant Cell Tumor of the Breast: A Case Report and Literature Review"],"prefix":"10.1002","volume":"53","author":[{"given":"Fei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Ultrasound The First Hospital of Jiaxing\/Affiliated Hospital of Jiaxing University  Jiaxing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Jia","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The First Hospital of Jiaxing\/Affiliated Hospital of Jiaxing University  Jiaxing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan\u2010Ze","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pathology Jiaxing Hospital of Traditional Chinese Medicine  Jiaxing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14265"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20190624-04"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711070106"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197206)29:6<1518::AID-CNCR2820290616>3.0.CO;2-#"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10396-018-0891-0"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-008-3774-y"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2023.107952"},{"issue":"1","key":"e_1_2_8_9_1","first-page":"2393","article-title":"Primary Giant Cell Tumour of the Breast With Recurrence: A Rare Case Report","volume":"26","author":"Suleman F. 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