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This comprehensive review of the literature published over the last 20\u2009years, with an emphasis on the role of prenatal ultrasound in predicting postnatal outcomes in a fetus with AMC, showed that ultrasound is a crucial tool to diagnose and prognosticate this rare disease. Different clinical manifestations of AMC are associated with different outcomes. Postnatal prognosis depends on several factors. Future multicenter prospective studies are necessary to investigate the prognostic factors associated with AMC.<\/jats:p>","DOI":"10.1002\/jcu.23983","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T20:57:44Z","timestamp":1743368264000},"page":"1131-1139","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal Diagnosis and Prognostic Factors in Fetuses With Arthrogryposis Multiplex Congenita\u2014A Systematic Review"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5924-8463","authenticated-orcid":false,"given":"Mario Brock","family":"Leao","sequence":"first","affiliation":[{"name":"University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9356-116X","authenticated-orcid":false,"given":"Marianna Facchinetti","family":"Brock","sequence":"additional","affiliation":[{"name":"University of the Amazon State  Manaus Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7701-6834","authenticated-orcid":false,"given":"Jorge Roberto Di Tommaso","family":"Leao","sequence":"additional","affiliation":[{"name":"University of the Amazon State  Manaus Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5314-7231","authenticated-orcid":false,"given":"Gianpaolo","family":"Grisolia","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Carlo Poma Hospital, AST Mantova  Mantova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5436-0185","authenticated-orcid":false,"given":"Mario","family":"Lituania","sequence":"additional","affiliation":[{"name":"Preconceptional and Prenatal Pathophysiology, Department of Obstetrics and Gynecology, E.O. 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