{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:40:52Z","timestamp":1791020452077,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To construct nomograms for both sides of the fetal fornix\u2013hippocampus complex (FHC) length and hippocampus height between 18\u2009+\u20090 and 23\u2009+\u20096\u2009weeks of gestation using two\u2010dimensional sonography. Additionally, we evaluated the effects of laterality, fetal sex, and maternal iron deficiency anemia on these measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective cross\u2010sectional study of 223 singleton pregnancies between 18\u2009+\u20090 and 23\u2009+\u20096\u2009weeks of gestation. The FHC length and hippocampus height were measured on both sides in the parasagittal cranial plane of the fetus by 2D ultrasonography. Measurements from 30 women with iron deficiency anemia, out of 223 patients, were compared to those of normal controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nomograms for FHC length and hippocampus height were constructed, showing a strong correlation with gestational age. No significant differences were found between the right and left side FHC lengths or hippocampus heights (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05), nor between male and female fetuses (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). The FHC lengths (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) and hippocampus heights (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) of fetuses in anemic and non\u2010anemic pregnancies also showed no significant differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>2D ultrasound morphology of the fetal hippocampus and fornix during the second trimester is not significantly different between pregnancies with iron deficiency anemia and nonanemic women.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.24008","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T05:48:06Z","timestamp":1744782486000},"page":"1288-1295","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fetal Fornix\u2013Hippocampus Complex and Hippocampus Height Measurements Between 18 and 24\u2009Weeks of Gestation and the Effect of Maternal Iron Deficiency Anemia"],"prefix":"10.1002","volume":"53","author":[{"given":"Gorkem","family":"Arica","sequence":"first","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Perinatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru Alici","family":"Davutoglu","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Perinatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Buldum","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Perinatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dogu","family":"Kucuksuleymanoglu","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Perinatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samira","family":"Najmeddin","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Perinatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riza","family":"Madazli","sequence":"additional","affiliation":[{"name":"Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology, Division of Perinatology Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"issue":"2","key":"e_1_2_8_2_1","first-page":"317","article-title":"Summary, Number 233","volume":"138","author":"ACOG Practice Bulletin Anemia in Pregnancy","year":"2021","journal-title":"ObstetGynecol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960401)367:2<274::AID-CNE9>3.0.CO;2-2"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1619690"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-010-0673-x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-017-0023-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1909"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.07.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200008000-00009"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.110.000190"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22004"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0361267"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.03.006"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2011.30.12.1613"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20128"},{"issue":"3","key":"e_1_2_8_16_1","first-page":"525","article-title":"Embryology of the Human Fetal Hippocampus: MR Imaging, Anatomy, and Histology","volume":"18","author":"Kier E. 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