{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:44:57Z","timestamp":1788281097965,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2025,9]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n To compare the diagnostic accuracy of O\u2010RADS (Ovarian Reporting and Data System) and IOTA (international Ovarian Tumor Analysis group) simple rules (SR) and ADNEX (Assessment of Different NEoplasias in the adnexa) model for discriminating benign from malignant adnexal masses using meta\u2010analysis.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A systematic search of studies comparing O\u2010RADS with SR and\/or ADNEX in the same set of patients with an adnexal mass was performed in Medline, Web of Science, and Scopus databases from January 2020 to September 2023. Quality was assessed using the QUADAS\u20102 tool. Quantitative meta\u2010analysis was performed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Nine articles comprising 3924 women (3979 adnexal masses) were ultimately included after exclusions. Three studies compared O\u2010RADS versus SR, three studies compared O\u2010RADS versus ADNEX, and three studies compared all three methods. The risk of bias was high for patient selection in QUADAS\u20102 in all studies. Six studies compared O\u2010RADS versus SR; no significant differences were found (pooled sensitivity and specificity of O\u2010RADS and IOTA SR were 94.0% and 77.0%, and 91.0% and 87.0%, respectively.\n p<\/jats:italic>\n \u2009=\u20090.2204). Six studies compared O\u2010RADS versus ADNEX; no significant differences were found (pooled sensitivity and specificity of O\u2010RADS classification system and ADNEX were 95.0% and 79.0%, and 91.0% and 88.0%, respectively.\n p<\/jats:italic>\n \u2009=\u20090.2307).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n O\u2010RADS classification has a similar diagnostic performance to IOTA SR and ADNEX for discriminating benign and malignant adnexal masses.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jcu.24048","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T06:10:23Z","timestamp":1745907023000},"page":"1574-1583","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of the Diagnostic Performance of Ovarian Adnexal Reporting Data System (O\u2010\n RADS<\/scp>\n ) With\n IOTA<\/scp>\n Simple Rules and\n ADNEX<\/scp>\n Model for Classifying Adnexal Masses: A Head\u2010To\u2010Head Meta\u2010Analysis"],"prefix":"10.1002","volume":"53","author":[{"given":"Gisela","family":"Almeida","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Centro Hospitalar de Setubal Setubal Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Bort","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Castell\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9700-0853","authenticated-orcid":false,"given":"Juan Luis","family":"Alc\u00e1zar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine Clinica Universidad de Navarra Pamplona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019191150"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07143-7"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.766"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-022-08803-6"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-06937-z"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.14366\/usg.21237"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.24777"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9062010"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101438.2007.01035.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15834"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2007.02.040"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13071307"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018172271"},{"key":"e_1_2_9_15_1","unstructured":"SEER (Surveillance Epidemiology and End Results Program).2023.\u201cSEER Stat Fact Sheets: Ovarian Cancer.\u201dhttps:\/\/seer.cancer.gov\/statfacts\/html\/ovary.html. 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