{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:32:40Z","timestamp":1790087560315,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Targeted neonatal echocardiography (TNE) is increasingly utilized by neonatologists to assess hemodynamics, particularly when cardiology\u2010performed echocardiography (CPE) is unavailable. It is crucial that TNE screens and identifies structural abnormalities. This study evaluated the agreement between TNE and CPE in detecting significant congenital heart disease (CHD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, single\u2010center cohort study included infants who underwent TNE between 2015 and 2019 and had at least one complete CPE before discharge. Infants with a known CHD diagnosis prior to TNE were excluded. Atrial septal defects (ASD) &lt;\u20093\u2009mm, peripheral pulmonary stenosis, and patent ductus arteriosus were excluded. Agreement between TNE and CPE was assessed using correlation coefficients and kappa statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 339 infants with 954 TNE scans were included. TNE identified CHD in 41 infants, with all but one (a false positive bicuspid aortic valve) confirmed by CPE. TNE missed CHD in 29 infants (31 lesions), mostly minor, with only one case (pulmonary stenosis) requiring intervention. The overall agreement was 91.15%, with a kappa of 0.68 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>TNE demonstrated good agreement with CPE in detecting significant CHD in a low\u2010risk neonatal population. Most missed lesions were minor, underscoring the importance of ongoing training and quality assurance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcu.70032","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T03:15:06Z","timestamp":1755054906000},"page":"81-87","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessing the Utility of Targeted Neonatal Echocardiography for Congenital Heart Disease Detection: Retrospective Cohort Analysis"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4422-8248","authenticated-orcid":false,"given":"Eyad","family":"Bitar","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"},{"name":"Department of Pediatrics, Division of Neonatology Queen's University  Kingston Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimann","family":"Surak","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rula","family":"Agarushi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"},{"name":"Department of Pediatrics Thompson General Hospital  Thompson Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Pepper","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt","family":"Hicks","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Hyderi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa K.","family":"Hornberger","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatrics Cardiology University of Alberta  Edmonton Alberta Canada"},{"name":"Department of Obstetrics &amp; Gynecology University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Eckersley","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatrics Cardiology University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumar","family":"Kumaran","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatal\u2010Perinatal Care (NICU) University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/266520"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2020.11.005"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2018.03.007"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390\u2010018\u20100082\u20100"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390\u2010018\u20100081\u20101"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2010.05.001"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895\u20104356(90)90158"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.33.10.1833"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390\u2010018\u20100076\u2010y"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2019.02.002"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000001129"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-018-0075-z"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2023.11.016"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jer181"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.15.06037"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442\u2010200x.2001.01342.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0130-y"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2017036"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1017\/S104795110400602X"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.100"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390\u2010018\u20100078\u20109"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.14797\/mdcj\u201014\u20101\u201060"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jped.2019.04.006"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T11:25:14Z","timestamp":1767612314000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.70032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/jcu.70032"],"URL":"https:\/\/doi.org\/10.1002\/jcu.70032","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]},"assertion":[{"value":"2025-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}