{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:44:53Z","timestamp":1784022293896,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2026,3]]},"abstract":"ABSTRACT<\/jats:title>\n \n Purpose<\/jats:title>\n \n Ebstein anomaly (EA) is a congenital heart disease that can cause intrauterine fetal death. Pulmonary valve stenosis or atresia (PS\/PA) and retrograde ductus arteriosus flow (RDAF) are important factors leading to a poor prognosis, but the causes of its formation are still unclear. This study aimed to assess the correlation between left and right ventricular function and PS\/PA and RDAF in fetuses with EA using MAPSE and TAPSE\n Z<\/jats:italic>\n \u2010score values measured by free angle M\u2010mode (FAM) echocardiography.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This retrospective cohort study of 34 EA and 68 normal fetuses was enrolled. Differences in\n Z<\/jats:italic>\n \u2010score values were compared between the control, EA with and without PS\/PA groups, and between EA\u2010PS\/PA with and without RDAF group. Correlation analysis was performed between\n Z<\/jats:italic>\n \u2010score values with the ratio of inner diameter of the pulmonary to the aortic valve annulus (PA\/AO) and RDAF.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The differences in\n Z<\/jats:italic>\n \u2010score values were significant (\n p<\/jats:italic>\n \u2009<\u20090.001) between three groups.\n Z<\/jats:italic>\n \u2010score values were lower in EA\u2010PS\/PA with RDAF compared to the without RDAF group (\n p<\/jats:italic>\n \u2009<\u20090.05).\n Z<\/jats:italic>\n \u2010scores were all positively correlated with PA\/AO in the EA group (\n p<\/jats:italic>\n \u2009<\u20090.05), and negatively correlated with RDAF in the EA\u2010PS\/PA group (\n p<\/jats:italic>\n \u2009<\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Decreased ventricular function of EA fetus is related to the formation of PS\/PA. After the formation of PS\/PA, the degree of damage to ventricular function is not related to the diameter of the pulmonary artery; it is related to the formation of RDAF.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jcu.70122","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T06:24:37Z","timestamp":1762323877000},"page":"691-697","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Study on the Correlation Between Ventricular Function Evaluated by\n Z<\/i>\n \u2010Score of Atrioventricular Annular Plane Systolic Excursion and Pulmonary Artery Abnormality and Retrograde Ductus Arteriosus Flow in Fetuses With Ebstein Anomaly"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9447-4597","authenticated-orcid":false,"given":"Xianfeng","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Ultrasound Medicine Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital Zhejiang University College of Medicine Zhejiang Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shanghai University of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2019.07.008"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.015839"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.11.013"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.23695"},{"issue":"11","key":"e_1_2_8_6_1","first-page":"1010","article-title":"Z\u2010Score Analysis of Mitral Annular Plane Systolic Excursion in Normal Fetuses With Fetal Echocardiography","volume":"31","author":"Guo X. F.","year":"2015","journal-title":"Chinese Journal of Ultrasound Medicine"},{"issue":"11","key":"e_1_2_8_7_1","first-page":"951","article-title":"Z\u2010Score Analysis of Tricuspid Annular Plane Systolic Excursion in Normal Fetuses With Fetal Echocardiography","volume":"24","author":"Guo X. F.","year":"2015","journal-title":"Chinese Journal of Ultrasonography"},{"issue":"2","key":"e_1_2_8_8_1","first-page":"121","article-title":"Application of Annular Plane Systolic Excursion z\u2010Score in Evaluation of Heart Systolic Function of Fetuses With Heart Failure","volume":"26","author":"Guo X. F.","year":"2017","journal-title":"Chinese Journal of Ultrasonography"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-020-02347-6"},{"issue":"4","key":"e_1_2_8_10_1","first-page":"304","article-title":"Evaluation of Right Ventricular Function in Fetuses With Ebstein Anomaly Using Tei Index Combined With Tricuspid Annual Systolic Excursion and Fraction Area Change","volume":"35","author":"Liu X. C.","year":"2016","journal-title":"Journal of Cardiovascular & Pulmonary Diseases"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33883"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000504979"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-020-01412-z"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165174"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20302"},{"issue":"6","key":"e_1_2_8_16_1","first-page":"489","article-title":"Preliminary Study on Fetal Heart Morphology and Function in Pulmonary Stenosis and Pulmonary Atresia Using Fetal Heart Quantification","volume":"33","author":"Zhang X. M.","year":"2024","journal-title":"Chinese Journal of Ultrasonography"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70122","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcu.70122","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:48:45Z","timestamp":1772966925000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.70122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,4]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/jcu.70122"],"URL":"https:\/\/doi.org\/10.1002\/jcu.70122","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,4]]},"assertion":[{"value":"2025-02-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}