{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:29:46Z","timestamp":1790983786278,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to investigate the variations in junctional zone (JZ) ultrasonographic parameters using three\u2010dimensional transvaginal ultrasound (3D\u2010TVS) across different age groups and evaluate their diagnostic potential for adenomyosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of 120 patients who underwent 3D\u2010TVS examinations. Participants were categorized into adenomyosis and healthy control groups, with the control group further stratified into three age\u2010based subgroups (20+, 30+, and 40+ years). Quantitative JZ parameters were meticulously measured, including maximum thickness (JZmax), minimum thickness (JZmin), thickness difference (JZdif, calculated as JZmax\u2009\u2212\u2009JZmin), myometrial thickness adjacent to JZmax, and the ratio of JZmax to adjacent myometrial thickness. Statistical comparisons were performed among groups, and receiver operating characteristic (ROC) curves were constructed to determine the area under the curve (AUC) m\u00fcllerian values for adenomyosis diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Age\u2010stratified analysis revealed no statistically significant differences in JZ parameters among control subgroups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05), indicating minimal age\u2010related variations in JZ characteristics. Compared to healthy controls, adenomyosis patients demonstrated significantly elevated values in JZmax, JZmin, JZdif, and the myometrial thickness adjacent to JZmax (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). ROC analysis yielded AUC values of 0.85 for JZmax, 0.84 for myometrial thickness adjacent to JZmax, 0.79 for JZdif, and 0.76 for JZmin. Optimal diagnostic performance was achieved at JZmax\u2009\u2265\u20090.45 cm, demonstrating 77% sensitivity and 89% specificity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>3D\u2010TVS with 3D reconstruction technology enables clear visualization of uterine coronal section and accurate quantification of JZ parameters. These findings support the clinical utility of 3D\u2010TVS in the diagnostic evaluation of adenomyosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcu.70167","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T06:30:42Z","timestamp":1767421842000},"page":"1113-1121","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Application Value of Transvaginal Three\u2010Dimensional Ultrasonography in the Diagnosis of Adenomyosis of the Uterus"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3517-9361","authenticated-orcid":false,"given":"Mengyu","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ultrasound The Affiliated Hospital of Hangzhou Normal University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Zong","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The Affiliated Hospital of Hangzhou Normal University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoman","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The Affiliated Hospital of Hangzhou Normal University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5459-9408","authenticated-orcid":false,"given":"Hebin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The Affiliated Hospital of Hangzhou Normal University  Hangzhou 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