{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T20:57:40Z","timestamp":1788123460168,"version":"build-2803163510"},"reference-count":6,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This case report describes a prenatal diagnosis of sirenomelia sequence at 12\u2009weeks and 4\u2009days of gestation using two\u2010dimensional (2D) and three\u2010dimensional (3D) ultrasound. The case highlights the importance of First Trimester ultrasound screening and the value of 3D ultrasound in early diagnosis. The etiology of this condition is discussed, with a focus on its potential association with embryonic layer development abnormalities. Ultimately, the patient opted for termination of pregnancy. This report provides valuable clinical experience in the early ultrasound diagnosis of sirenomelia sequence and discusses the importance of its ultrasound manifestations and clinical management.<\/jats:p>","DOI":"10.1002\/jcu.70223","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:34:46Z","timestamp":1773286486000},"page":"1534-1537","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal Ultrasound Diagnosis of Sirenomelia Sequence in First Trimester: A Case Report"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6566-8186","authenticated-orcid":false,"given":"Kepeng","family":"Shao","sequence":"first","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Provincial Maternity and Child\u2010Care Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8342-6080","authenticated-orcid":false,"given":"Zhiyu","family":"Feng","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Provincial Maternity and Child\u2010Care Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shurong","family":"Ding","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Second People\u2019s Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanzhao","family":"Wang","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Provincial Maternity and Child\u2010Care Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5380-2943","authenticated-orcid":false,"given":"Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Provincial Maternity and Child\u2010Care Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4384-9701","authenticated-orcid":false,"given":"Tiangang","family":"Li","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Provincial Maternity and Child\u2010Care Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3308-2404","authenticated-orcid":false,"given":"Bin","family":"Ma","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Center, Gansu Provincial Maternity and Child\u2010Care Hospital  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404\u2010008\u20100619\u20102"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2023.109189"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.24975"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5146\/tjpath.2020.01491"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.62103"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404\u2010013\u20102847\u20103"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70223","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcu.70223","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T10:45:59Z","timestamp":1783161959000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.70223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,11]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/jcu.70223"],"URL":"https:\/\/doi.org\/10.1002\/jcu.70223","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,11]]},"assertion":[{"value":"2025-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}