{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:18:17Z","timestamp":1788445097765,"version":"build-2803163510"},"reference-count":9,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 17\u2010year\u2010old male presented with intermittent palpitations for 6\u2009months, acutely worsening over 24\u2009h. Physical examination revealed Marfanoid features (arachnodactyly, positive thumb\/wrist signs, pectus carinatum) and cardiac abnormalities (irregular rhythm, 3\/6 systolic murmur with mid\u2010late click). Echocardiography demonstrated: (1) Aortic sinu (AS) dilation (41\u2009mm); (2) Bileaflet mitral valve prolapse (Barlow's Disease) with myxomatous degeneration (anterior leaflet 3.8\u2009mm, posterior 4.2\u2009mm); (3) Mitral annular disjunction (MAD, 13\u2009mm gap). Transesophageal echo revealed left atrial appendage sluggish flow (\u201csmoke\u2010like echo\u201d) without thrombus. CTA confirmed aortic root aneurysm (42\u2009mm) and right hydronephrosis. Electrocardiogram demonstrated paroxysmal atrial flutter. Diagnoses included Marfan syndrome (Ghent criteria), Barlow's Disease with MAD, paroxysmal atrial flutter, and obstructive hydronephrosis. The multidisciplinary team recommended staged interventions. Following catheter ablation for atrial flutter, the patient declined further procedures. Subsequent follow\u2010up showed clinical stability.<\/jats:p>","DOI":"10.1002\/jcu.70251","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T11:54:42Z","timestamp":1775649282000},"page":"1736-1740","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound Diagnosis of Marfan Syndrome Complicated by Barlow Disease With Mitral Annular Disjunction: A Case Report"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1753-3995","authenticated-orcid":false,"given":"Xiao\u2010zheng","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Ultrasound, Renmin Hospital Hubei University of Medicine  Shiyan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xaio\u2010zhuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Renmin Hospital Hubei University of Medicine  Shiyan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010ping","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Renmin Hospital Hubei University of Medicine  Shiyan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5603-6172","authenticated-orcid":false,"given":"Zhao\u2010jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Renmin Hospital Hubei University of Medicine  Shiyan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-8-53"},{"issue":"6","key":"e_1_2_9_3_1","first-page":"335","article-title":"Cardiovascular Characteristics in Marfan Syndrome and Their Relation to the Genotype","volume":"71","author":"De Backer J.","year":"2009","journal-title":"Verhandelingen \u2010 Koninklijke Academie voor Geneeskunde van Belgi\u00eb"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.07.070"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2021.09.004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67789-6"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14051423"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(79)90429-0"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd8020023"},{"issue":"4","key":"e_1_2_9_10_1","first-page":"453","article-title":"Marfan Syndrome: From Basic Research to Clinical Decision\u2010Making","volume":"29","author":"Zhang H.","year":"2023","journal-title":"Lingnan Journal of Cardiovascular Diseases"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70251","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcu.70251","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.70251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T13:57:29Z","timestamp":1788443849000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.70251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,8]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/jcu.70251"],"URL":"https:\/\/doi.org\/10.1002\/jcu.70251","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,8]]},"assertion":[{"value":"2025-04-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}