{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:07:46Z","timestamp":1789020466513,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n The effect of intralesional gas on diagnostic disagreement between chest radiography (CXR) and lung ultrasound (LUS) in pediatric pneumonia is uncertain. In the present study, computed tomography (CT) was used as the reference standard. Bronchial aeration signs within consolidation were graded. The influence of these signs on diagnostic sensitivity and on associations with inflammatory markers was assessed.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective study was performed in 110 children with confirmed pneumonia. Patients were assigned to three grades according to CT morphology of bronchial air signs: Grade 1 (solid\/punctate;\n n<\/jats:italic>\n \u2009=\u200935), Grade 2 (segmental\/discontinuous;\n n<\/jats:italic>\n \u2009=\u200935), and Grade 3 (arborized;\n n<\/jats:italic>\n \u2009=\u200940). Diagnostic sensitivity was calculated for CXR and LUS. Inflammatory markers (lactate dehydrogenase (LDH), C\u2010reactive protein (CRP), white blood cell (WBC) count), and clinical outcomes (bronchoscopy rate, length of hospital stay) were compared across grades.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n As lung air content increased from Grade 1 to Grade 3, chest X\u2010ray sensitivity significantly decreased from 94.3% to 82.5% (\n p<\/jats:italic>\n \u2009<\u20090.01), whereas LUS sensitivity remained stable (>\u200992%) across all grades (\n p<\/jats:italic>\n \u2009>\u20090.05). Concurrently, Grade 1 consolidation was most conspicuous on CXR. It was also associated with the highest inflammatory markers (LDH 380\u2009\u00b1\u200980\u2009U\/L; CRP 65.4\u2009\u00b1\u200918.5\u2009mg\/L; WBC 14.5\u2009\u00b1\u20093.5\u2009\u00d7\u200910\n 9<\/jats:sup>\n \/L). The bronchoscopy rate was highest in Grade 1 (82.9%) and lowest in Grade 3 (12.5%,\n p<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Bronchial air trapping was identified as a major confounder for\n CXR<\/jats:styled-content>\n but not for\n LUS<\/jats:styled-content>\n . High diagnostic performance was maintained by\n LUS<\/jats:styled-content>\n for consolidation with abundant bronchial air trapping (Grade 3). Consolidation with minimal bronchial air trapping (Grade 1) was associated with severe airway obstruction and a high requirement for early bronchoscopic intervention.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jcu.70394","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T05:51:08Z","timestamp":1789019468000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multimodal Imaging Evaluation of Pulmonary Consolidation in Children: Diagnostic Value of Lung Ultrasound Based on\n CT<\/scp>\n Air Bronchogram Grading and Its Correlation With Inflammatory Biomarkers and Clinical Prognosis"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0683-5292","authenticated-orcid":false,"given":"Haodong","family":"Wang","sequence":"first","affiliation":[{"name":"Ordos Central Hospital Ordos China"},{"name":"Baotou Medical College Baotou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Xu","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yandong","family":"Xu","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoli","family":"Zhang","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpu","family":"Qu","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5497-579X","authenticated-orcid":false,"given":"Jin","family":"Gao","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3879-0031","authenticated-orcid":false,"given":"Shuai","family":"Gao","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanhao","family":"Guo","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8173-0368","authenticated-orcid":false,"given":"Rong","family":"Wu","sequence":"additional","affiliation":[{"name":"Ordos Central Hospital Ordos China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","first-page":"e77158","article-title":"Ultrasonography Compared to Computed Tomography in Pediatric Complicated Pneumonia: Beyond Radiation","volume":"17","author":"Ajmire P.","year":"2025","journal-title":"Cureus"},{"issue":"1","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1186\/s13054-024-05102-y","article-title":"Nuts and Bolts of Lung Ultrasound: Utility, Scanning Techniques, Protocols, and Findings in Common Pathologies","volume":"28","author":"Beshara M.","year":"2024","journal-title":"Critical Care"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15147"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40477\u2010021\u201000600\u2010z"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247\u2010020\u201004750\u2010w"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s44158\u2010024\u201000206\u2010x"},{"issue":"7","key":"e_1_2_10_8_1","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.21037\/tp-24-36","article-title":"Could Lung Ultrasound Be a Valid Alternative to Ionizing Radiation or a Complementary Diagnostic Choice in Pediatric Respiratory Diseases?","volume":"13","author":"Caroselli C.","year":"2024","journal-title":"Translational Pediatrics"},{"key":"e_1_2_10_9_1","doi-asserted-by":"crossref","first-page":"9328177","DOI":"10.1155\/2024\/9328177","article-title":"Clinical Features and Biomarkers for Early Prediction of Refractory \n Mycoplasma pneumoniae\n Pneumonia in Children","volume":"2024","author":"Chen Q.","year":"2024","journal-title":"Emergency Medicine International"},{"issue":"2","key":"e_1_2_10_10_1","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/ppul.25760","article-title":"Pediatric Pneumonia (PedPne) Lung Ultrasound Score and Inflammatory Markers: A Pilot Study","volume":"57","author":"Ciuca I. 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