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The current study examined the psychometric properties and established clinical cutoffs for the parent\u2010report version of the Toronto Obsessive\u2013Compulsive Scale (TOCS), a 21\u2010item rating scale of obsessive\u2013compulsive traits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Participants ranged in age from 6 to 21\u00a0years old and had a primary diagnosis of OCD (<jats:italic>n<\/jats:italic>\u00a0=\u00a0350, 50% female), attention\u2010deficit\/hyperactivity disorder (ADHD) (<jats:italic>n<\/jats:italic>\u00a0=\u00a0820, 25% female), autism spectrum disorder (ASD) (<jats:italic>n<\/jats:italic>\u00a0=\u00a0794, 22% female), or were typically developing controls (<jats:italic>n<\/jats:italic>\u00a0=\u00a0391, 51% female). Confirmatory factor analyses, internal consistency reliability, and convergent and divergent validity of the TOCS were examined in the OCD group. Using various scoring approaches, receiver operating characteristic (ROC) analyses were used to establish a clinical cut\u2010off by splitting the OCD group into a discovery sample (166 OCD cases, 164 controls) and a validation sample (184 OCD cases, 227 controls). Classification accuracy and TOCS scores were compared across OCD, ADHD, and ASD groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The psychometric properties of the TOCS were confirmed. ROC analyses across TOCS scoring approaches in the discovery sample indicated excellent diagnostic discrimination (AUC \u22650.95, sensitivity 77%\u201392%, specificity 92%\u201398%). Established cutoffs, when applied in the independent validation sample of OCD cases and controls, showed an overall classification accuracy of 85%\u201390%. The TOCS total score and symptom count showed good discrimination of OCD from ADHD (AUC \u22650.86) and ASD (AUC \u22650.81). The OCD group scored significantly higher on all TOCS dimensions (except Hoarding) than the ADHD and ASD groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The TOCS is a reliable and valid rating scale with strong sensitivity and specificity in discriminating OCD cases from controls, as well as from ASD and ADHD. It\u00a0is a quantitative OCD measure with important clinical and research applications, with particular relevance for cross disorder phenotyping and population\u2010based studies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcv2.12056","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T11:30:57Z","timestamp":1638531057000},"source":"Crossref","is-referenced-by-count":7,"title":["Clinical validation of the parent\u2010report Toronto Obsessive\u2013Compulsive Scale (TOCS): A pediatric open\u2010source rating scale"],"prefix":"10.1002","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7223-7854","authenticated-orcid":false,"given":"Laura J.","family":"Lambe","sequence":"first","affiliation":[{"name":"Program of Neurosciences and Mental Health Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8955-6528","authenticated-orcid":false,"given":"Christie L.","family":"Burton","sequence":"additional","affiliation":[{"name":"Program of Neurosciences and Mental Health Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3455-9887","authenticated-orcid":false,"given":"Evdokia","family":"Anagnostou","sequence":"additional","affiliation":[{"name":"Bloorview Research Institute Holland Bloorview Kids Rehabilitation Hospital  Toronto Ontario Canada"},{"name":"Department of Pediatrics University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Kelley","sequence":"additional","affiliation":[{"name":"Department of Psychology Queen's University  Kingston Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Nicolson","sequence":"additional","affiliation":[{"name":"Schulich School of Medicine and Dentistry University of Western Ontario  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stelios","family":"Georgiades","sequence":"additional","affiliation":[{"name":"Department of Psychiatry &amp; 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