{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T07:15:16Z","timestamp":1788160516676,"version":"build-2803163510"},"reference-count":56,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["ZIAMH002781"],"award-info":[{"award-number":["ZIAMH002781"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["ZIAMH002969"],"award-info":[{"award-number":["ZIAMH002969"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCPP Advances"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Decades of youth psychotherapy research have demonstrated the efficacy of cognitive behavioral therapy (CBT) on targeted symptoms using standardized, retrospective clinician\u2010, child\u2010, and parent\u2010report. Advancements in digital technologies can be leveraged to capture granular symptom change in patients' natural environments. While CBT is tailored to treat specific diagnosis\u2010perpetuating mechanisms, it remains unknown whether such effects may carry over to non\u2010targeted symptoms, which could have important treatment implications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We examined targeted and non\u2010targeted symptom change in two separate exposure\u2010based CBT trials: one trial for anxiety (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a092) and one for irritability (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a039). Youth in both trials completed ecological momentary assessment (EMA) pre\u2010, mid\u2010, and post\u2010treatment;\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a057 healthy volunteer youth completed EMA at matching time intervals. Each EMA interval lasted for 7\u00a0days (3 prompts\/day). We used multilevel modeling to examine changes in symptoms across time (e.g.,\u00a0pre, mid, post).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We observed frustration to decrease over time in both youth with anxiety (non\u2010targeted symptom) and irritability (targeted symptom). We observed anger to decrease in youth with irritability only (targeted symptom), and worry did not change significantly over time in either group. Healthy volunteer youth showed low, stable levels of symptoms across time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Findings highlight frustration as a potential key transdiagnostic symptom; frustration improves in both youth with clinical anxiety and with irritability over the course of exposure\u2010based CBT. Demonstrating specificity, anger in youth seeking treatment for irritability, but not anxiety, improved over time. While additional research is needed to better understand measurement of in vivo worry, results support using EMA to monitor symptom change during CBT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcv2.70160","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T06:38:04Z","timestamp":1788158284000},"source":"Crossref","is-referenced-by-count":0,"title":["Ecological momentary assessment of targeted and non\u2010targeted symptom changes in clinical anxiety and irritability among children and adolescents receiving cognitive behavioral therapy"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0286-9319","authenticated-orcid":false,"given":"Lauren M.","family":"Henry","sequence":"first","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4745-649X","authenticated-orcid":false,"given":"Meghan E.","family":"Byrne","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Modell","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Massac","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5945-1637","authenticated-orcid":false,"given":"Krystal","family":"Lewis","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5811-7442","authenticated-orcid":false,"given":"Simone","family":"Haller","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0424-5094","authenticated-orcid":false,"given":"Reut","family":"Naim","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"},{"name":"School of Psychological Sciences Tel\u2010Aviv University  Tel\u2010Aviv Israel"},{"name":"Sagol School of Neuroscience Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6546-5584","authenticated-orcid":false,"given":"Katharina","family":"Kircanski","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"},{"name":"Department of Psychology University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4301-9516","authenticated-orcid":false,"given":"Daniel S.","family":"Pine","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9859-4702","authenticated-orcid":false,"given":"Melissa A.","family":"Brotman","sequence":"additional","affiliation":[{"name":"Emotion and Development Branch National Institute of Mental Health (NIMH)  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2013"},{"key":"e_1_2_11_3_1","first-page":"108","volume-title":"Handbook of research methods for studying daily life","author":"Barta W. 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