{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T08:40:26Z","timestamp":1793868026811,"version":"4.6.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["440557\/2016\u20100"],"award-info":[{"award-number":["440557\/2016\u20100"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J of Devlp Neuroscience"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To characterize the spectrum of brain damages presented in children affected by Congenital Zika Syndrome (CZS), verify the existence of a co\u2010occurrence pattern of these damages and discuss possible implications for the neuropsychological development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Descriptive, quantitative, individualized, and cross\u2010sectional study using secondary sources. We selected 136 children with CZS from the database of the Center of Strategic Information on Health Vigilance of the Municipal Office of Salvador, Brazil. We conducted descriptive and multiple correspondence analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the set of analyzed variables, microcephaly (51.5%), ventriculomegaly (57.4%), and brain calcifications (77.2%) were identified as the most frequent. The multiple correspondence analysis showed that the combination of these three variables (32.4%) was what better represented the spectrum of brain damages in the Central Nervous System.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Damage in the sensory\u2010motor, cognitive and language development, as well as neurodevelopmental disorders, are described in the literature as impairments associated, either isolated or combined, with these damages, and it is worth highlighting that, in combined brain damages, impairments tend to be more severe. The findings of this study may contribute to understanding the repercussions of CZS on the neuropsychological development of children affected by the epidemic.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jdn.10016","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T13:15:02Z","timestamp":1581945302000},"page":"189-196","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Brain abnormalities on neuroimaging in Children with Congenital Zika Syndrome in Salvador, Brazil, and its possible implications on neuropsychological development"],"prefix":"10.1002","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8824-4688","authenticated-orcid":false,"given":"Paula","family":"Sanders Pereira Pinto","sequence":"first","affiliation":[{"name":"UNIFACS Universidade Salvador Salvador Brazil"},{"name":"Instituto de Sa\u00fade Coletiva (UFBA) Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9257-1278","authenticated-orcid":false,"given":"Thalita Madeira","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Instituto de Sa\u00fade Coletiva (UFBA) Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4832-7059","authenticated-orcid":false,"given":"Lucas","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Instituto de Sa\u00fade Coletiva (UFBA) Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6056-050X","authenticated-orcid":false,"given":"Mirela Maisa da Silva","family":"Souza","sequence":"additional","affiliation":[{"name":"Instituto de Sa\u00fade Coletiva (UFBA) Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5600-5287","authenticated-orcid":false,"given":"George Anderson","family":"Alves dos Santos","sequence":"additional","affiliation":[{"name":"Instituto de Sa\u00fade Coletiva (UFBA) Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5432-1174","authenticated-orcid":false,"given":"Cristiane Wanderley","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Secretaria Municipal de Sa\u00fade de Salvador Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5963-2166","authenticated-orcid":false,"given":"Let\u00edcia Marques","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Instituto de Humanidades Artes e Ci\u00eancias da UFBA Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6798-2059","authenticated-orcid":false,"given":"Guilherme Sousa","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz Brazil"},{"name":"Faculdade de Medicina da UFBA Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1500-8294","authenticated-orcid":false,"given":"Darci Neves","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Instituto de Sa\u00fade Coletiva (UFBA) Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,18]]},"reference":[{"issue":"021304","key":"e_1_2_11_2_1","first-page":"1","article-title":"Neurodevelopment of 24 children born in Brazil with Congenital Zika Syndrome in 2015: A case series study","volume":"8","author":"Alves L. 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