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Serotonergic abnormalities have been discovered in SIDS infants in the zone of the medulla oblongata, which is known to control cardio\u2010respiratory function. SIDS establishes a connection between depression, learning difficulties and behavioural disorders. Prenatal nicotine intake during the second trimester affects the dopaminergic neurological system, making the foetal brain more susceptible to nicotine and developing ADHD symptoms not just in a foetus but in adolescents also. Prenatal nicotine exposure alters the neurological route of neurotransmitters, acetylcholine and dopamine. Nicotine enhances neuronal activity in adults but desensitizes these processes in babies and young children exposed prenatally. The impact of a neurotoxin like nicotine is determined by the amount and duration of exposure. Continued exposure throughout pregnancy will influence a wide range of activities in the neurodevelopment, whereas exposure confined to a single stage of pregnancy may only affect the processes that are forming at that stage. To decrease the effect of nicotine on neonates due to maternal smoking strategies like nicotine replacement therapy (NRT), folic acid treatment and other behavioural treatments have been studied. Hence, this review focuses on the impact of exposure to nicotine on neonates, which results in various neurological consequences and smoking cessation therapies.<\/jats:p>","DOI":"10.1002\/jdn.10163","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T09:42:19Z","timestamp":1639647739000},"page":"3-18","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Neurological repercussions of neonatal nicotine exposure: A review"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8207-8685","authenticated-orcid":false,"given":"Joyal","family":"Xavier","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research, Export Promotion Industrial Park (EPIP)  Hajipur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9021-6547","authenticated-orcid":false,"given":"Sanjiv","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research, Export Promotion Industrial Park (EPIP)  Hajipur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research, Export Promotion Industrial Park (EPIP)  Hajipur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Ravichandiran","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research, Export Promotion Industrial Park (EPIP)  Hajipur India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,30]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2004.12.001"},{"key":"e_1_2_13_3_1","unstructured":"Adams P. 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