{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:49:26Z","timestamp":1791384566143,"version":"4.3.3"},"reference-count":95,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J of Devlp Neuroscience"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    No approved treatments currently exist for the core symptoms of autism spectrum disorder (ASD), prompting clinicians and families to seek alternative approaches, including dietary and nutritional interventions. The Mediterranean diet (MeDi), characterized by a high intake of antioxidant and anti\u2010inflammatory components, is associated with improved health outcomes and reduced risk of chronic diseases. A key element of the MeDi is extra virgin olive oil (EVOO), which is rich in bioactive phenolics, including oleocanthal, oleuropein and hydroxytyrosol. Through its antioxidant and anti\u2010inflammatory actions, EVOO may contribute to regulating pathological processes in both the central nervous system (CNS) and the gastrointestinal tract, offering a promising avenue for pharmacological and nutritional intervention in children with ASD. This pilot study investigated the effects of a three\u2010month intervention combining the MeDi with EVOO supplementation on ASD symptoms. Ten children diagnosed with ASD aged 5.00\u201311.7\u2009years, all boys, were recruited from Northern Greece. The changes in social interaction and communication were evaluated using standardized instruments: the Social Responsiveness Scale (SRS), Word Finding Vocabulary Test (WFVT), Autism Diagnostic Interview\u2010Revised (ADI\u2010R) and the Sensory Profile (SP). Paired\u2010sample\n                    <jats:italic>t<\/jats:italic>\n                    \u2010tests revealed significant improvements post\u2010intervention in SRS (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.034), ADI\u2010R A (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.008), WFVT (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.020) and ADI\u2010R B (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.022) scores. These findings suggest that EVOO supplementation may reduce the severity of social deficits and enhance communication skills in children with ASD.\n                  <\/jats:p>","DOI":"10.1002\/jdn.70181","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:49:31Z","timestamp":1791380971000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of High\u2010Phenolic Extra Virgin Olive Oil on Sensory Processing in Children With Autism Spectrum Disorder: A Pilot Study"],"prefix":"10.1002","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8674-0870","authenticated-orcid":false,"given":"Despoina","family":"Papastavridou","sequence":"first","affiliation":[{"name":"Neuroscience and Neurodegenerative diseases Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5035-4187","authenticated-orcid":false,"given":"Eleni","family":"Baldimtsi","sequence":"additional","affiliation":[{"name":"Neuroscience and Neurodegenerative diseases Aristotle University of Thessaloniki  Thessaloniki Greece"},{"name":"1st Department of Neurology, School of Medicine Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aikaterini","family":"Katsiana","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy University of Western Macedonia  Ptolemaida Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2072-8010","authenticated-orcid":false,"given":"Magda","family":"Tsolaki","sequence":"additional","affiliation":[{"name":"Neuroscience and Neurodegenerative diseases Aristotle University of Thessaloniki  Thessaloniki Greece"},{"name":"Laboratory of Neurodegenerative Diseases, Center for Interdisciplinary Research and Innovation Aristotle University of Thessaloniki (CIRI\u2014AUTh)  Thessaloniki Greece"},{"name":"Greek Association of Alzheimer's Disease and Related Disorders (GAADRD)  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.9b00175"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.5409\/wjcp.v10.i3.15"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25031914"},{"key":"e_1_2_13_5_1","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803\u2010007\u20100459\u20100"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2020.07.002"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803\u2010020\u201004595\u20100"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20107610.2005.01546.x"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920\u2010014\u20100437\u20100"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2015.07.025"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.11.010"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035\u2010019\u201001742\u20102"},{"issue":"11","key":"e_1_2_13_14_1","first-page":"459","article-title":"A Comparison of the Sensory Profile Scores of Children With Autism and an Age\u2010 and Gender\u2010Matched Sample","volume":"66","author":"Brockevelt B. 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