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Biochemical analyses have focussed on the relatively low molecular weight glycoproteins likely to be found in more serous\u2010type granules of the ampulla and not on the very high MW glycoproteins typical of mucus and represented in the isthmus by morphological evidence of mucus secretion. Quantitatively, secretion from the ampulla is likely to predominate, because of its huge surface area compared with the isthmus. But functional closure of the isthmus under the influence of estradiol in the absence of progesterone means that it is the isthmus where luminal secretions accumulate\u2014and where mucus glycoproteins will exert their most important effects on spermatozoa ascending the reproductive tract, and then on fertilized ova en route to the uterus. Further study of the extracellular, intraluminal, carbohydrate\u2010rich environment of the oviductal isthmus, especially in humans, is likely to prove rewarding. Sampling of these secretions is now feasible using transvaginal, transuterine fallopian tube catheters that are in clinical use. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jemt.1070320104","type":"journal-article","created":{"date-parts":[[2005,2,23]],"date-time":"2005-02-23T16:19:42Z","timestamp":1109175582000},"page":"29-49","source":"Crossref","is-referenced-by-count":11,"title":["Ultrastructure and histochemistry of acid mucus glycoproteins in the estrous mammal oviduct"],"prefix":"10.1002","volume":"32","author":[{"given":"Robert P. S.","family":"Jansen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,4]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"28","article-title":"Structure of gastrointestinal mucus glycoproteins and the viscous and gel\u2010forming properties of mucus","volume":"34","author":"Allen A.","year":"1978","journal-title":"Br. Med. 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