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The imaging system is built around a fast, sensitive sCMOS camera and rapid switchable LED light source. It features complete automation of all the steps of the imaging process and contains built\u2010in feedback loops to ensure proper operation. The imaging system is intended as a back end to the RABiT\u2014a robotic platform for radiation biodosimetry. It is intended to automate image acquisition and analysis for four biodosimetry assays for which we have developed automated protocols: The Cytokinesis Blocked Micronucleus assay, the \u03b3\u2010H2AX assay, the Dicentric assay (using PNA or FISH probes) and the RABiT\u2010BAND assay. <jats:italic>Microsc. Res. 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