{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:03:57Z","timestamp":1790442237322,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T00:00:00Z","timestamp":1434499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microscopy Res &amp;amp; Technique"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We describe the use of a rabbit maxillary sinus model, characterized by thin osseous tissue and low bone density, for the evaluation of surface\u2010treated implants by histologically and histomorphometrically comparing the osseointegration patterns depending on the surface treatment methods. Twenty rabbits were randomly assigned to two groups of 10 animals, one receiving 5 \u00d7 3 mm customized implants (machined, MA or sandblasted and acid etched, SLA) placed in sinus and the other receiving implants placed in a tibia. Histological observation of the implant placed in sinus shows relatively more active new bone formation, characterized by trabecular bone pattern underneath the cortical bone in sinus as compared with that in tibia. Histomorphometric analysis in the rabbits receiving implants in a tibia, the NBIC (%) associated with the SLA surface implant was greater than that associated with the MA implant at 2 weeks (55.63\u2009\u00b1\u20098.65% vs. 47.87\u2009\u00b1\u200910.01%; <jats:italic>P &gt;<\/jats:italic> 0.05) and at 4 weeks (61.76\u2009\u00b1\u20099.49% vs. 42.69\u2009\u00b1\u200910.97%; <jats:italic>P &lt;<\/jats:italic> 0.05). Among rabbits receiving implants in a sinus, the NBIC (%) associated with the SLA surface implant was significantly greater than that associated with the MA surface implant both at 2 weeks (37.25\u2009\u00b1\u20097.27% vs. 20.98\u2009\u00b1\u20096.42%; <jats:italic>P &lt;<\/jats:italic> 0.05) and at 4 weeks (48.82\u2009\u00b1\u20096.77% vs. 31.51\u2009\u00b1\u20099.14%; <jats:italic>P &lt;<\/jats:italic> 0.05). As a result, we suggest that the maxillary sinus model is an appropriate animal model for assessing surface\u2010treated implants and may be utilized for the evaluation of surface\u2010treated implants in poor bone quality environment. <jats:italic>Microsc. Res. Tech. 78:697\u2013706, 2015<\/jats:italic>. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jemt.22527","type":"journal-article","created":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T14:28:30Z","timestamp":1434551310000},"page":"697-706","source":"Crossref","is-referenced-by-count":5,"title":["A rabbit maxillary sinus model with simultaneous customized\u2010implant placement: Comparative microscopic analysis for the evaluation of surface\u2010treated implants"],"prefix":"10.1002","volume":"78","author":[{"given":"Sang\u2010Hyun","family":"Park","sequence":"first","affiliation":[{"name":"Department of Oral Science Research Center Yonsei University College of Dentistry Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyunmin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics Oral Science Research Center, Yonsei University College of Dentistry Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Bae","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dental Biomaterials and Bioengineering Yonsei University College of Dentistry Seoul Republic of Korea"},{"name":"Department of Stomatology Affiliated Hospital of Yanbian University Yanji Jilin Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenghao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dental Biomaterials and Bioengineering Yonsei University College of Dentistry Seoul Republic of Korea"},{"name":"Department of Stomatology Affiliated Hospital of Yanbian University Yanji Jilin Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamiyandori","family":"Otgonbold","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Orthodontics Health Science University Mongolia Ulaanbaatar Mongolia"},{"name":"Department of Oral Biology Yonsei University College of Dentistry Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jang\u2010Gi","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Orthodontics Health Science University Mongolia Ulaanbaatar Mongolia"},{"name":"Department of Oral Biology Yonsei University College of Dentistry Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Soo","family":"Han","sequence":"additional","affiliation":[{"name":"The Institute for the 3Rs &amp; Department of Laboratory Animal Medicine, College of Veterinary Medicine &amp; the Institute for the Veterinary Medicine Konkuk University Seoul Republic of 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