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Sixty human dentin samples were eroded <jats:italic>in vitro<\/jats:italic> and assigned into six groups (<jats:italic>n<\/jats:italic>\u2009=\u200910) according to the <jats:italic>in situ<\/jats:italic> surface treatment and number of cycling days: 4% TiF<jats:sub>4<\/jats:sub> gel applied once (TiF<jats:sub>4<\/jats:sub>1), twice (TiF<jats:sub>4<\/jats:sub>2), or three times (TiF<jats:sub>4<\/jats:sub>3) followed by 2, 4, and 6 days of erosive\/abrasive <jats:italic>in situ<\/jats:italic> cycling, respectively. Control groups (no treatment) were subjected to 2 (C1), 4 (C2), and 6 (C3) days of erosive\/abrasive <jats:italic>in situ<\/jats:italic> cycling only. A seventh group (<jats:italic>n<\/jats:italic>\u2009=\u200910) was comprised by <jats:italic>in vitro<\/jats:italic> uneroded samples (UN), subjected to 6 days of <jats:italic>in situ<\/jats:italic> erosive\/abrasive cycling. Each cycling day consisted on six erosive (0.5% citric acid, pH 2.6) and one abrasive events. Environmental scanning electron microscopy micrographs were taken. For all groups, blinded examiners assessed dentin tubules occlusion using visual scores (0\u2014unoccluded, 1\u2014partially occluded by granular deposits, 2\u2014partially occluded by reduction in tubular lumen into diamond shape, 3\u2014completely occluded) on images captured prior and after the <jats:italic>in situ<\/jats:italic> phase. Scheirer\u2010Ray\u2010Hare test demonstrated that treatments significantly affected tubule occlusion (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Dunn's test showed that tubule occlusion in TiF<jats:sub>4<\/jats:sub>3 was significantly higher than in C1. Tubule occlusion in remaining groups did not differ from that observed in groups TiF<jats:sub>4<\/jats:sub>3 and C1. Tubule occlusion was significantly higher after <jats:italic>in situ<\/jats:italic> phase. It may be suggested that TiF<jats:sub>4<\/jats:sub>, when applied three times, was able to positively change tubule occlusion of dentin samples.<\/jats:p>","DOI":"10.1002\/jemt.22915","type":"journal-article","created":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T08:04:37Z","timestamp":1501488277000},"page":"1182-1188","source":"Crossref","is-referenced-by-count":4,"title":["TiF<sub>4<\/sub> gel effects on tubular occlusion of eroded\/abraded human dentin"],"prefix":"10.1002","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5117-0232","authenticated-orcid":false,"given":"Ta\u00eds Fonseca","family":"Mantilla","sequence":"first","affiliation":[{"name":"School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo SP 05508\u2010000 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Vieira da","family":"Silva","sequence":"additional","affiliation":[{"name":"School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo SP 05508\u2010000 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thayanne Monteiro","family":"Ramos\u2010Oliveira","sequence":"additional","affiliation":[{"name":"School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo SP 05508\u2010000 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia Pedroso","family":"Turssi","sequence":"additional","affiliation":[{"name":"S\u00e3o Leopoldo Mandic Institute and Dental Research Center Campinas SP 13045\u2010755 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha Sim\u00f5es","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Institute of Energy and Nuclear Research University of S\u00e3o Paulo S\u00e3o Paulo SP 05508\u2010000 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Moreira de","family":"Freitas","sequence":"additional","affiliation":[{"name":"School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo SP 05508\u2010000 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2013.08.018"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2010.09.007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33254"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.1997.tb00233.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720150127"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720140124"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2009.09.012"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2009.00617.x"},{"key":"e_1_2_6_10_1","first-page":"351","article-title":"Dental erosion as oral disease. 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