{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:22:42Z","timestamp":1783948962892,"version":"3.55.0"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T00:00:00Z","timestamp":1545350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004612","name":"Funda\u00e7\u00e3o Arauc\u00e1ria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004612","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microscopy Res &amp; Technique"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Bauhinia forficata<\/jats:italic> is a medicinal plant that has flavonoid components with hypoglycemic, antioxidant, hepatoprotective, antibacterial, antiviral and anti\u2010inflammatory action. Aim of this study is to evaluate the action of <jats:italic>B. forficata<\/jats:italic> alcoholic extract in the male genital system of adult male Wistar rats. For that, 20 adult male Wistar rats were distributed into two experimental groups: the <jats:italic>B. forficata<\/jats:italic> group, receiving <jats:italic>B. forficata<\/jats:italic> alcoholic extract (0.1 ml\/10 g body weight\/day) on alternate days, and the control group, receiving just the vehicle for 30\u2009days straight both via gavage. On the 31st day, the animals were euthanized, and the testis and epididymis were collected for histopathological, biochemical, morphometric, and sperm count analysis. Mass spectrometry identified new compounds in the extract: trans\u2010caffeic acid, liquiritigenin, gallocatechin, and 2,4,6\u2010trihydroxyphenanthren\u20102\u2010glycoside. Biochemical analysis showed higher total cholesterol levels in the testis and lower <jats:italic>malondialdehyde<\/jats:italic> levels in the testis and epididymis, in the <jats:italic>B. forficata<\/jats:italic> group. The mast cell count showed a reduction in degranulated mast cells in the caput region of the epididymis, in the <jats:italic>B. forficata<\/jats:italic> group. The luminal compartment of the caput and the epithelial of the epididymis cauda were reduced, whereas the stromal region of the epididymis caput was increased in the <jats:italic>B. forficata<\/jats:italic> group, compared with the control group. The testicular tissue was less impaired, considering that all the histological analyses were similar to the control. We believe that <jats:italic>B. forficata<\/jats:italic> alcoholic extract in the male genital system showed antioxidant action, especially in the epididymal tissue.<\/jats:p>","DOI":"10.1002\/jemt.23175","type":"journal-article","created":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T12:12:01Z","timestamp":1545394321000},"page":"345-351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Alcohol extract of <i>Bauhinia forficata<\/i> link reduces lipid peroxidation in the testis and epididymis of adult Wistar rats"],"prefix":"10.1002","volume":"82","author":[{"given":"Carolina Ferreira","family":"Sampaio","sequence":"first","affiliation":[{"name":"General Biology Department, Biological Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicla Renata","family":"Lucchetta","sequence":"additional","affiliation":[{"name":"General Biology Department, Biological Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"},{"name":"Pharmaceutical Sciences Department, Health Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula Franco","family":"Punhagui","sequence":"additional","affiliation":[{"name":"General Biology Department, Biological Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"},{"name":"General Pathology Department, Biological Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe Rodrigues","family":"Banedetti","sequence":"additional","affiliation":[{"name":"Biology and Technology Department State University of North Paran\u00e1 \u2013 UENP  Bandeirantes Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilton Syogo","family":"Arakawa","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Department, Health Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio Rodrigues Ferreira","family":"Seiva","sequence":"additional","affiliation":[{"name":"Biology and Technology Department State University of North Paran\u00e1 \u2013 UENP  Bandeirantes Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6043-1131","authenticated-orcid":false,"given":"Glaura Scantamburlo Alves","family":"Fernandes","sequence":"additional","affiliation":[{"name":"General Biology Department, Biological Sciences Center State University of Londrina \u2013 UEL  Londrina Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2006.03.001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-865020160060000008"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(96)00351-6"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986711795656063"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmn055"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2009.06.007"},{"key":"e_1_2_8_8_1","unstructured":"Facility G. 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