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Based on the Thylstrup and Fejerskov index, 80 teeth were randomly divided equally into four groups: TFI 0, sound dentin; TFI 1\u20133, mild fluorosis; TFI 4\u20135, moderate fluorosis; and TFI 6\u20139, severe fluorosis. Each group was randomized into five subgroups. After preparing the dentin hypersensitivity model of DF, the dentin was pretreated as follows, Subgroup 1: deionized water (Control group); Subgroup 2: 1% BAG; Subgroup 3: 5% BAG; Subgroup 4: 10% BAG, and Subgroup 5: 20% BAG. Stochastically one specimen was selected from each subgroup for scanning electron microscope and energy dispersive spectrometer analysis. After being made of resin\u2013tooth bonding samples, the remains were in water bath at 37\u2009\u00b0C for 24\u2009hr. Subsequently, samples from each subgroup were randomly selected to test MSBS without aging, or after a thermocycle of 5,000 and 10,000 times, respectively. The fracture modes were analyzed. Compared with the group of 1% BAG and Control, the exposure area of tubules in 5%, 10%, and 20% BAG group had significant difference (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). MSBS results indicated that there were significant differences between 10% BAG with other groups. The 20% BAG group showed the lowest MSBS among all groups. Pretreatment of 10% BAG solution may be conductive to enhance the bond strength of DF, while 20% BAG solution adversely.<\/jats:p>","DOI":"10.1002\/jemt.24026","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T02:35:48Z","timestamp":1639449348000},"page":"1663-1670","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of <scp>45S5<\/scp> bioactive glass on the microshear bond strength of dental fluorosis"],"prefix":"10.1002","volume":"85","author":[{"given":"Xiaoyu","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Prosthodontics Hospital of Stomatology Affiliated to Southwest Medical University  Luzhou Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics Hospital of Stomatology Affiliated to Southwest Medical University  Luzhou 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