{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:26:19Z","timestamp":1760660779913,"version":"build-2065373602"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microscopy Res &amp; Technique"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>At 22nd day of fetal development, the primordial anlage of mandibular gland was first noticed as a solid epithelial bud from oral epithelium. The terminal buds were arranged in the form of clusters with undifferentiated epithelial cells and terminated in a bulb like structure in 28\u2010day\u2010old fetus. The lumenization and branching of the main cord was noticed at 35th day. The primary septa, which divide the glandular mass into lobes was observed from 53rd day onwards which resulted in the formation of distinct lobulation at 58th day. At 61st day, the capsule formation was initiated by the aggregation of mesenchymal tissue. The terminal tubules differentiated to form the secretory end pieces and the tubular portion leads to the formation of intercalated and striated ducts at 98th day. Predominantly mucous types of acinar cells were seen from 108th day onwards. The number of lobules increased with steep increase in parenchyma from 128th day onwards. Micrometrical studies revealed that the mean diameter of acinar cells and all ducts was increased with the advancement of age and the significant differences were observed between groups. Localization of acidic and neutral mucopolysaccharides was observed in mucous cells and goblet cells.<\/jats:p><\/jats:sec><jats:sec><jats:title>Research Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>The primordial anlage of mandibular salivary gland was seen at 22nd day. Lobulation of gland was appeared at 53rd day of development, however; it was completed at 58th day.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>At 98th day, the terminal tubules differentiated to form the secretory end pieces. The parenchyma of the gland showed predominantly mucous type of cells from 108th day onwards.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Myoepithelial cells were first appeared as flattened basal cells initially around the developing acinar cells at 132nd day.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Localization of acidic as well as neutral mucopolysaccharides was observed in mucous cells and goblet cells.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Fine lipid droplets were observed in intralobular as well as interlobular connective tissue, however; phospholipids were observed in the cell membrane of secretory cells and ducts.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/jemt.24585","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T06:14:49Z","timestamp":1715235289000},"page":"2241-2249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Developmental events in the mandibular salivary gland of Indian sheep (<i>Ovis aries<\/i>): Morphological and histochemical studies"],"prefix":"10.1002","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3203-9845","authenticated-orcid":false,"given":"Amandeep","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Veterinary Anatomy Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS)  Hisar Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simran","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Animal Genetics and Breeding Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS)  Hisar Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Opinder","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy Guru Angad Dev Veterinary and Animal Sciences University (GADVASU)  Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,9]]},"reference":[{"volume-title":"Current problems in surgery","year":"1981","author":"Attie J. 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