{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:38:04Z","timestamp":1790221084862,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:00:00Z","timestamp":1718150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microscopy Res &amp;amp; Technique"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>In the current study, we are focusing on the microanatomical structure of quail caecum during the prehatching time to try to understand the function and the role of each cell\u2010built quail caecum reaching how caecum plays an essential role in immunity and absorption. The morpho\u2010developmental features of the quail caecum were described in detail daily from the third incubation day (ID) till hatching time, investigating the gross morphology, microscopic, and ultrastructure using light and scanning electron microscope. The embryonic caecum appeared grossly as two lateral outpocketings with blinded ends, emerging laterally at the junction between the small and large intestine (the ileocaecal junction). The primordia of two caeca, represented by two lateral swellings from the hindgut on the fourth ID, continued growing till the day of hatching, where the caecal wall consisted of three apparent layers: mucosa, musculosa, and serosa. At the time of hatching, the quail caecum was still not fully mature and will continue growing posthatching. The findings in this study can be applied in further studies intended to understand the physiological mechanisms of the caecum during prehatching and posthatching periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Research Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Caecum is one of the hindgut derivatives that started as two lateral swellings.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The caecal wall consisted of three layers; mucosa, musculosa, and serosa.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The caecum plays an essential role in immunity maintenance.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Caecum continues to grow posthatching as it is not fully mature at hatching time.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/jemt.24632","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T07:20:49Z","timestamp":1718176849000},"page":"2540-2554","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Developmental morpho\u2010analysis of the caecum in Japanese quail embryos (<i>Coturnix coturnix japonica<\/i>)"],"prefix":"10.1002","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6822-1454","authenticated-orcid":false,"given":"Fatma","family":"Abdelhakeem","sequence":"first","affiliation":[{"name":"Department of Anatomy and Embryology, Faculty of Veterinary Medicine South Valley University  Qena Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.24146"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-52335-x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.32441\/ijms.6.3.5"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10735-022-10071-z"},{"key":"e_1_2_12_6_1","volume-title":"Atlas of chick development","author":"Bellairs R.","year":"2005"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781444318777.ch42"},{"key":"e_1_2_12_8_1","first-page":"93","article-title":"The avian cecum: A review","volume":"107","author":"Clench M. 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