{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:30:42Z","timestamp":1792510242739,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":44,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. exp. orthop."],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose\/Hypothesis<\/jats:title>\n                    <jats:p>The purpose was to evaluate the impact of coronal or sagittal alignment on patient\u2010reported outcomes after primary anterior cruciate ligament reconstruction (ACLR). The hypothesis was that coronal or sagittal alignment would not significantly influence 2\u2010year outcomes after a primary ACLR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Eighty patients with a mean age of 30.9 were included in this retrospective case series. Patients who underwent primary ACLR and at least 2 years of follow\u2010up completed the International Knee Documentation Committee survey, knee injury and osteoarthritis outcome score, Tegner activity level and the lysholm knee scoring scale. Scores were compared between varus, neutral and valgus alignments, as well as patients with a posterior tibial slope \u226512\u00b0 or\u2009&lt;12\u00b0. Independent two\u2010tailed\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests determined significant differences between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The primary outcome was patients with varus alignment had significantly decreased postoperative International Knee Documentation Committee survey (80.18) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010), knee injury and osteoarthritis outcome score: Sports and rec (75.40) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036) and Tegner activity level (6.00) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) scores compared to patients with neutral alignment (88.11, 85.37 and 7.61, respectively). No other groups showed a significant difference. A secondary outcome showed no significant difference between increasing coronal alignment deformity from neutral (180\u00b0) and patient\u2010reported outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The primary outcome demonstrated significantly higher postoperative International Knee Documentation Committee Survey, knee injury and osteoarthritis outcome score: sports and recreation, and Tegner score in the neutral compared to the varus alignment groups, with knee injury and osteoarthritis outcome score: sports and recreation and Tegner score surpassing the minimally clinically important difference. No significant differences were observed between other coronal or sagittal groups. These findings suggest that varus alignment may be associated with clinically meaningful differences in patient outcomes compared to neutral alignment after primary ACLR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective case series.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jeo2.70558","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T11:12:22Z","timestamp":1763118742000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Varus aligned patients have decreased patient reported International Knee Documentation Committee, knee injury and osteoarthritis outcome score sports scores and Tegner activity levels compared to neutral aligned patients in primary anterior cruciate ligament reconstructions"],"prefix":"10.1002","volume":"12","author":[{"given":"Claire J.","family":"Knowlan","sequence":"first","affiliation":[{"name":"Creighton University School of Medicine Omaha Nebraska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke V.","family":"Tollefson","sequence":"additional","affiliation":[{"name":"Twin Cities Orthopedics Edina Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jace R.","family":"Otremba","sequence":"additional","affiliation":[{"name":"University of North Dakota School of Medicine and Health Sciences Grand Forks North Dakota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas I.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Orthopedics Northwest Yakima Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"LaPrade","sequence":"additional","affiliation":[{"name":"Twin Cities Orthopedics Edina Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9823-2306","authenticated-orcid":false,"given":"Robert F.","family":"LaPrade","sequence":"additional","affiliation":[{"name":"Twin Cities Orthopedics Edina Minnesota 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