{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T19:02:37Z","timestamp":1789844557050,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":58,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. exp. orthop."],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Previous studies have reported magnetic resonance imaging (MRI) changes in the donor\u2010site defect size following anterior cruciate ligament reconstruction (ACLR) using the middle third of the patellar tendon (mid\u2010third patellar tendon ACLR); however, no corresponding reports exist for ACLR using the medial third of the patellar tendon (medial\u2010third patellar tendon ACLR). This study aimed to assess the changes in donor\u2010site defect size postoperatively in medial\u2010third ACLR patients and hypothesized a clinically relevant MRI change within the first year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty\u2010two consecutive patients underwent MRI examinations to measure the donor\u2010site defect size (\u2018gap\u2019 signal) and laterally remaining tendon size (\u2018normal tendon\u2019 signal) at two time points: 14 (\u00b15) days and 7.9 (\u00b12.0) months postoperatively. The primary outcome was the post\u2010pre difference of the \u201cgap\u201d signal. Wilcoxon signed rank test assessed the post\u2013pre difference of the \u2018gap\u2019 signal, while robust linear regression examined the effect of either age at surgery or follow\u2010up time on the post\u2013pre difference of the \u2018gap\u2019 signal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The primary finding was a significant reduction in the \u2018gap\u2019 signal [\u22129.2\u2009mm (95% CI: \u221212.3; \u22126.7)] between 2 weeks and ~8 months (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The \u2018normal tendon\u2019 signal did not change significantly [1.6\u2009mm (95% CI: \u22120.5; 3.3),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.237]. Age at surgery had a negative, statistically nonsignificant effect on donor\u2010site \u2018gap\u2019 signal difference (\u22122.24 [95% CI: \u22125.59; 0.60],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.106). In addition, follow\u2010up time had a negative, statistically nonsignificant effect on donor\u2010site \u2018gap\u2019 signal difference (\u22120.97 [95% CI: \u22122.98; 4.14],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.571). Eight of 22 patients had no detectable \u2018gap\u2019 signal at 8 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The most important finding for this study is a significant decrease in the donor\u2010site defect along with an undetectable \u2018gap\u2019 that was verified for ~36% of the sample at a minimum mean follow\u2010up of ~8 months. The laterally remaining \u2018normal tendon\u2019 signal remained unchanged. Neither age at surgery nor follow\u2010up time had an impact on the healing of the donor\u2010site defect. From a clinical perspective our findings suggest that the medial\u2010third patellar tendon autograft has a high healing capacity after harvesting, already at a mean follow\u2010up of ~8 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jeo2.70571","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T09:10:37Z","timestamp":1764321037000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the donor site defect after harvesting the medial third of the patellar tendon in ACL reconstruction: An MRI study"],"prefix":"10.1002","volume":"12","author":[{"given":"Jim","family":"Georgoulis","sequence":"first","affiliation":[{"name":"1st Department of Orthopaedic Surgery National and Kapodistrian University of Athens Athens Greece"},{"name":"Department of Orthopedics, Orthopaedic Sports Medicine Center of Ioannina University of Ioannina Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Savvidou","sequence":"additional","affiliation":[{"name":"1st Department of Orthopaedic Surgery National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paraskevi","family":"Kosta","sequence":"additional","affiliation":[{"name":"Radiology Department, Medical School University Hospital of Ioannina Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kostas","family":"Patras","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Orthopaedic Sports Medicine Center of Ioannina University of Ioannina Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Argyropoulou","sequence":"additional","affiliation":[{"name":"Radiology Department, Medical School University Hospital of Ioannina Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panayiotis","family":"Papagelopoulos","sequence":"additional","affiliation":[{"name":"1st Department of Orthopaedic Surgery National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasios","family":"Georgoulis","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Orthopaedic Sports Medicine Center of Ioannina University of Ioannina Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546520968289"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2017.11.032"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(98)70014-3"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354658000800602"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2016.09.020"},{"key":"e_1_2_11_7_1","volume-title":"Mathematical statistics with resampling and R","author":"Chihara LM","year":"2022"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659202000317"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.76B2.8113275"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/17453674.1997.11744742"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/23259671241265840"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v7.i10.638"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325967120925482"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2020.05.025"},{"key":"e_1_2_11_15_1","volume-title":"Arthroskopische versus offene Operationen","author":"Hertel P","year":"1994"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670050115"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670000132"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670050054"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781003039617"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2003.08.006"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659402200121"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325967120961082"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504265926"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2001.25957"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcot.2018.03.003"},{"issue":"317","key":"e_1_2_11_26_1","first-page":"162","article-title":"Reconstitution of the patellar tendon donor site after graft harvest","author":"Nixon RG","year":"1995","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325967117709735"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2012.08.003"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546519885148"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513509220"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2009.12.009"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659202000506"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546503258935"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023476"}],"container-title":["Journal of Experimental Orthopaedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jeo2.70571","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jeo2.70571","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jeo2.70571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T18:20:57Z","timestamp":1789842057000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1002\/jeo2.70571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/jeo2.70571"],"URL":"https:\/\/doi.org\/10.1002\/jeo2.70571","archive":["Portico"],"relation":{},"ISSN":["2197-1153","2197-1153"],"issn-type":[{"value":"2197-1153","type":"print"},{"value":"2197-1153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-06-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70571"}}