{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T15:04:05Z","timestamp":1775919845055,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":83,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. exp. orthop."],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Large correction in opening wedge high tibial osteotomy (HTO) may lead to excessive joint line obliquity (JLO). This study hypothesized that the presence of an oblique joint line, defined by knee joint line obliquity (KJLO)\u2009&gt;\u20095\u00b0 and\/or medial proximal tibial angle (MPTA)\u2009&gt;\u200994\u00b0, was associated with poorer functional outcomes and lower survival rates following HTO at long\u2010term follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective study included 83 patients who underwent a medial opening wedge HTO with at least 5 years of follow\u2010up. Complete pre\u2010 and postoperative radiographic parameters (hip\u2013knee\u2013ankle angle [HKA], MPTA, lateral distal femoral angle [LDFA], KJLO, joint line convergence angle [JLCA]) and functional outcomes (Knee injury and Osteoarthritis Outcome Score [KOOS], International Knee Society Score [IKS], Subjective Knee Value [SKV]) were analysed. Excessive JLO was defined by a KJLO\u2009\u2265\u20095\u00b0 and\/or an MPTA\u2009&gt;\u200994\u00b0. An independent Student's\n                      <jats:italic>t<\/jats:italic>\n                      test was then performed to compare functional scores and angular measurements between groups. Functional results and revision\u2010free survival were analysed according to JLO, using the Kaplan\u2013Meier method for survival analysis. The mean follow\u2010up was 12.3\u2009\u00b1\u20093.3 years (5\u201319).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The HKA, MPTA, JLCA and KJLO angles varied significantly (\u0394HKA\u2009=\u20097.8\u00b0\u2009\u00b1\u20093.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Functional scores showed no significant difference between patients with or without JLO. Five\u2010 and 10\u2010year survival rates were 86% and 71%, respectively, with no difference based on JLO (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.500). Smoking, age\u2009&gt;\u200955 years, Ahlb\u00e4ck stage III osteoarthritis and out\u2010of\u2010target postoperative alignment (HKA\u2009&lt;\u2009180\u00b0 or &gt;\u2009183\u00b0) were identified as risk factors for conversion to total knee arthroplasty in multivariate Cox regression analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This retrospective analysis found no significant association between excessive JLO (KJLO\u2009\u2265\u20095\u00b0 and\/or MPTA\u2009&gt;\u200994\u00b0) and either survival or functional outcomes after medial opening wedge HTO at a mean follow\u2010up of 12 years. Factors negatively influencing survival after HTO were smoking, age\u2009&gt;\u200955 years, advanced osteoarthritis and out\u2010of\u2010target postoperative alignment. These findings should be confirmed by larger series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jeo2.70655","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T12:52:03Z","timestamp":1774443123000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lack of evidence for an effect of joint line obliquity after medial opening wedge high tibial osteotomy: A 12\u2010year single\u2010centre retrospective study"],"prefix":"10.1002","volume":"13","author":[{"given":"Lilia","family":"Gharbi","sequence":"first","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"},{"name":"ICARE Unit, C\u00f4te d'Azur University, Inserm, CNRS Valrose Institute of Biology Nice Provence\u2010Alpes\u2010C\u00f4te d'Azur France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Lopez","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Attas","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Bronsard","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9gis Bernard de","family":"Dompsure","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lolita","family":"Micicoi","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8279-880X","authenticated-orcid":false,"given":"Gr\u00e9goire","family":"Micicoi","sequence":"additional","affiliation":[{"name":"IULS\u2010University Institute for Locomotion and Sports, Pasteur 2 Hospital University C\u00f4te d'Azur Nice France"},{"name":"ICARE Unit, C\u00f4te d'Azur University, Inserm, CNRS Valrose Institute of Biology Nice Provence\u2010Alpes\u2010C\u00f4te d'Azur France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,25]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"7","article-title":"Osteoarthrosis of the knee. 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