{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:51:12Z","timestamp":1792083072607,"version":"4.4.0"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. exp. orthop."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Meniscal repair failure is a significant clinical concern, but existing literature treats it as a single outcome without differentiating timing. Early and late failures may represent mechanistically distinct phenomena; identifying their differential predictors could improve risk stratification and postoperative monitoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study used a national database to identify patients undergoing arthroscopic meniscal repair, including both isolated repairs and repairs performed with concomitant anterior cruciate ligament reconstruction, classified into early failure (reoperation &lt;365 days, approximating the conventional period of meniscal healing), late failure (\u2265365 days) or no failure. Cause\u2010specific Cox proportional hazards regression identified independent predictors of each failure type separately.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 38,003 patients, 3399 (8.9%) experienced failure (1996 early; 1403 late). A bimodal hazard pattern supported phenotypic distinction between groups. Early failure was independently predicted by female sex (hazard ratio [HR] 1.15), bucket\u2010handle tear (HR 1.30), traumatic mechanism (HR 1.14), concomitant microfracture (HR 1.54), hamstring autograft (HR 1.21) and single\u2010anchor repair (HR 1.28); three or more anchors were protective (HR 0.83). Late failure was uniquely predicted by knee osteoarthritis (HR 1.33), whereas increasing age was independently protective (HR 0.98\/year) as well as three or more anchors (HR 0.86). Among isolated meniscal repairs, partial meniscectomy was the most common reoperation in both groups, but more frequent in late failures (60.1% vs. 53.7%). Re\u2010repair was more common after early failure (22.5% vs. 16.1%), while TKA was more prevalent after late failure (9.8% vs. 5.4%). All reported associations and between\u2010group differences were statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early and late meniscal repair failures are distinct clinical phenotypes with differing risk factors and reoperation patterns. Early failure appears driven by mechanical and technical factors; late failure is more strongly associated with degenerative joint disease and host biology. These findings may inform individualised monitoring and risk stratification strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jeo2.70856","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T17:25:07Z","timestamp":1784568307000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Not all meniscal repair failures are equal: A comparison between early and late failure risk factors"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0427-9999","authenticated-orcid":false,"given":"Jacob W.","family":"McDevitt","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery Northwestern University Feinberg School of 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Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4435-9898","authenticated-orcid":false,"given":"Michael O.","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5801-0358","authenticated-orcid":false,"given":"Jake A.","family":"Morales","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9890-8954","authenticated-orcid":false,"given":"Vehniah K.","family":"Tjong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Northwestern University Feinberg School of Medicine Chicago Illinois 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