{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:51:31Z","timestamp":1792083091425,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":57,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. exp. orthop."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Lateral ankle sprain (LAS) is one of the most common musculoskeletal injuries associated with sensorimotor impairments that increase the risk of reinjury and chronic ankle instability. Early clinical assessment after acute LAS is often symptom\u2010guided rather than based on objective functional testing. This study aimed to identify the most sensitive functional impairments within the first weeks after injury and to determine cut\u2010off values that support structured clinical assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this cross\u2010sectional matched case\u2010control analysis, 36 individuals (14\u201341\u2009years) with MRI\u2010confirmed first\u2010time acute LAS were compared to 36 matched healthy controls. Patients (recruiting 01\/22\u201009\/24) were assessed 2\u20133 weeks post\u2010injury using patient\u2010reported outcomes, postural control, strength, range of motion (ROM), gait\/running kinematics and jump performance. Between\u2010group differences were analysed using\n                      <jats:italic>t<\/jats:italic>\n                      tests or Statistical Parametric Mapping. Receiver operating characteristic analyses were used to determine diagnostic cut\u2010off values. It was hypothesized that individuals with acute first\u2010time LAS would demonstrate clinically relevant deficits across functional domains compared with healthy controls, and that these parameters would allow the derivation of clinically useful cut\u2010off values.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Individuals with LAS demonstrated substantial impairments across several domains. The most discriminative parameters were Foot and Ankle Ability Measure (FAAM) Sport (effect size [ES] \u22124.09, cut\u2010off &lt;86) and Cumberland Ankle Instability Tool (CAIT) (ES \u22123.65; cut\u2010off &lt;26) (psychometry), Star Excursion Balance Test (SEBT) composite score (ES \u22121.22; cut\u2010off &lt;92.81) (postural control), concentric plantarflexion strength (ES \u22121.34; cut\u2010off &lt;2.24\u2009Nm\/kg) (strength), passive plantarflexion and total ROM (ES \u22122.29; cut\u2010off &lt;44\u00b0 and &lt;72\u00b0), transverse ankle kinematics during gait (ES 1.14; cut\u2010off &lt;\u221215\u00b0) (gait\/running) and drop jump contact time (ES 1.62; cut\u2010off &gt;0.23\u2009s) (jump performance). These measures formed a minimal multidimensional assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These parameters and cut\u2010off values enable objective, multidimensional assessment in the early phase after acute LAS and may facilitate impairment\u2010based rehabilitation beyond symptom\u2010guided evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, cross\u2010sectional matched pair\u2010study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jeo2.70892","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:41:05Z","timestamp":1787859665000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early functional deficits following first\u2010time acute lateral ankle sprain: A multidimensional assessment framework with clinically relevant cut\u2010off values"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1989-4641","authenticated-orcid":false,"given":"Janina","family":"Tennler","sequence":"first","affiliation":[{"name":"Department of Arthroscopic Surgery, Sports Traumatology and Sports Medicine BG Klinikum Duisburg Duisburg Germany"},{"name":"Athletikum Rhein Ruhr BG Klinikum Duisburg Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1932-2662","authenticated-orcid":false,"given":"Christian","family":"Raeder","sequence":"additional","affiliation":[{"name":"Department of Arthroscopic Surgery, Sports Traumatology and Sports Medicine BG Klinikum Duisburg Duisburg Germany"},{"name":"Athletikum Rhein Ruhr BG Klinikum Duisburg Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3347-323X","authenticated-orcid":false,"given":"Arthur","family":"Praetorius","sequence":"additional","affiliation":[{"name":"Department of Arthroscopic Surgery, Sports Traumatology and Sports Medicine BG Klinikum Duisburg Duisburg Germany"},{"name":"Athletikum Rhein Ruhr BG Klinikum Duisburg Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Colcuc","sequence":"additional","affiliation":[{"name":"Department of Arthroscopic Surgery, Sports Traumatology and Sports Medicine BG Klinikum Duisburg Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva S.","family":"Steinhausen","sequence":"additional","affiliation":[{"name":"Department of Trauma, Hand and Reconstructive Surgery University Hospital Essen Essen Germany"},{"name":"Department of Trauma and Reconstructive Surgery BG Klinikum Duisburg Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6641-5506","authenticated-orcid":false,"given":"Marcel","family":"Dudda","sequence":"additional","affiliation":[{"name":"Department of Trauma, Hand and Reconstructive Surgery University Hospital Essen Essen Germany"},{"name":"Department of Trauma and Reconstructive Surgery BG Klinikum Duisburg Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1902-9164","authenticated-orcid":false,"given":"Christian","family":"Schoepp","sequence":"additional","affiliation":[{"name":"Department of Arthroscopic Surgery, Sports Traumatology and Sports Medicine BG Klinikum Duisburg Duisburg Germany"},{"name":"Athletikum Rhein Ruhr BG Klinikum Duisburg Duisburg Germany"},{"name":"Department of Trauma, Hand and Reconstructive Surgery University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2008.2811"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/s18030719"},{"key":"e_1_2_14_4_1","unstructured":"Bloch H Klein C K\u00fchn N Luig P. 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