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At doses in excess of 0.1 \u03bcg\/kg, a secondary rise in arterial blood pressure was observed which could be abolished by bretylium, phentolamine or phenoxybenzamine.<\/jats:p><jats:p>Catecholamines did not affect the heart rate although a transient bradycardia due to reflex inhibition could be observed with adrenaline and noradrenaline. Catecholamines increased the cardiac contractile force through an \u03b1\u2010adrenergic mechanism which was blocked by phentolamine but not by propranolol. The relative potency was noradrenaline &gt; adrenaline\u226bisoprenaline. A \u03b2\u2010adrenergic receptor located in the branchial circulation led to vasodilation and decrease in transbranchial differential pressure. Both \u03b1\u2010(vasoconstriction) and \u03b2\u2010(vasodilation) adrenergic receptors were present in the systemic circulation.<\/jats:p><jats:p>Dopamine, 5\u2010HT, GABA and bradykinin caused bradycardia abolishable by vagotomy or atropine treatment. Angiotensin II was hypertensive but did not affect the heart rate nor the transbranchial differential pressure. Tyramine caused release of endogenous catecholamines. With repeated doses, tachyphylaxis to the drug was observed. Histamine was without any obvious cardiovascular effects in the eel.<\/jats:p>","DOI":"10.1002\/jez.1401960103","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T07:13:06Z","timestamp":1118473986000},"page":"13-26","source":"Crossref","is-referenced-by-count":60,"title":["The effects of acetylcholine, biogenic amines and other vasoactive agents on the cardiovascular functions of the eel, <i>Anguilla japonica<\/i>"],"prefix":"10.1002","volume":"196","author":[{"given":"D. K. O.","family":"Chan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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