{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T14:07:56Z","timestamp":1697897276944},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"vor","delay-in-days":8156,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Exp. Zool."],"published-print":{"date-parts":[[1983,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Microphthalmic white (Mi<jats:sup>wh<\/jats:sup>), when heterozygous, causes dilution of black fur to a uniform gray color. Mi<jats:sup>wh<\/jats:sup>\/+ also reduces the coloration of ear and tail skin. The present study, a quantitative assessment of the effects of Mi<jats:sup>wh<\/jats:sup>\/+ on cutaneous melanocytes, demonstrates that the primary effect of Mi<jats:sup>wh<\/jats:sup>\/+ on cutaneous pigmentation is to reduce the number of epidermal melanocytes. There is also indirect evidence that Mi<jats:sup>wh<\/jats:sup>\/+ reduces the rate of melanosome production within follicular melanocytes. These actions of Mi<jats:sup>wh<\/jats:sup>\/+ cause both lightened coloration of ear and tail skin and the deposition of fewer numbers of smaller melanosomes within the hair.<\/jats:p>","DOI":"10.1002\/jez.1402250217","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T02:34:03Z","timestamp":1118457243000},"page":"329-335","source":"Crossref","is-referenced-by-count":2,"title":["Effects of microphthalmic white (Mi<sup>wh<\/sup>) on the number and function of cutaneous melanocytes"],"prefix":"10.1002","volume":"225","author":[{"given":"Bruce M.","family":"Pratt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1401710311"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1964.tb14214.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330310312"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/oxfordjournals.jhered.a105681","article-title":"Mutant white mice: a new dominant autosomal mutant affecting coat color in Mus musculus","volume":"38","author":"Grobman A. B.","year":"1947","journal-title":"J. Hered."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12510302"},{"key":"e_1_2_1_7_1","first-page":"560","article-title":"Peroxidase, \u201cprotyrosinase,\u201d and the multiple forms of tyrosinase in mice","volume":"46","author":"Holstein T. J.","year":"1973","journal-title":"Yale J. Biol. Med."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.66.3.663"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1001\/archderm.1969.01610300106020","article-title":"Pigment transfer in mammalian epidermis","volume":"100","author":"Klaus S. N.","year":"1969","journal-title":"Arch. Dermatol."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.2307\/3572800"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1402200112"},{"key":"e_1_2_1_12_1","unstructured":"Rittenhouse E. W. (1965)Inherited variation in the fine structure of melanin granules in hair bulb melanocytes of the house mouse. Ph. D. Thesis University of Michigan."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12258559"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1093\/genetics\/31.3.327","article-title":"A quantitative histological study of the pigment found in the coat\u2010color mutants of the house mouse. I. Variable attributes of the pigment granules","volume":"31","author":"Russell E. S.","year":"1946","journal-title":"Genetics"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1093\/genetics\/33.3.228","article-title":"A quantitative histological study of the pigment found in the coat color mutants of the house mouse. II. Estimates of the total volume of pigment","volume":"33","author":"Russell E. 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Dermatol."},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S001667230003487X"}],"container-title":["Journal of Experimental Zoology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjez.1402250217","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jez.1402250217","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:18:11Z","timestamp":1697761091000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jez.1402250217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,2]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1983,2]]}},"alternative-id":["10.1002\/jez.1402250217"],"URL":"https:\/\/doi.org\/10.1002\/jez.1402250217","archive":["Portico"],"relation":{},"ISSN":["0022-104X","1097-010X"],"issn-type":[{"value":"0022-104X","type":"print"},{"value":"1097-010X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,2]]}}}