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Of ten mutants isolated, eight lose their motilities between 30\u00b0C and 33\u00b0C without prominent changes in body forms. The other two strains that are mainly described in this report are accompanied by alterations in body forms. One mutation, <jats:italic>cn<\/jats:italic>101, is recessive and an allele of <jats:italic>cha\u20101<\/jats:italic>. The <jats:italic>cn101<\/jats:italic> mutant shows reversible paralysis at 30\u00b0, accompanied by a hypercontracted and coiled body form. At the restrictive temperature, the strain is resistant to all tested inhibitors of acetylcholinesterase (AChE). Another mutation, designated <jats:italic>mah\u20102<\/jats:italic> (<jats:italic>cn110<\/jats:italic>), is a sex\u2010linked semidominant that is mapped as 0.6 map units left of <jats:italic>dpy\u20106<\/jats:italic>. The <jats:italic>cn110<\/jats:italic> mutant is rapidly paralyzed at the restrictive temperature and has a straight and rigid body form; the mutant rapidly recovers when the temperature is lowered. No disorganization of the muscle structure was detected by polarized light and electron microscopic inspection.<\/jats:p>","DOI":"10.1002\/jez.1402350313","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T06:33:57Z","timestamp":1118471637000},"page":"409-421","source":"Crossref","is-referenced-by-count":14,"title":["Temperature\u2010sensitive mutations causing reversible paralysis in <i>Caenorhabditis elegans<\/i>"],"prefix":"10.1002","volume":"235","author":[{"given":"Ryuji","family":"Hosono","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigeru","family":"Kuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Midsukami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,4,25]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1098\/rstb.1976.0085","article-title":"The pharynx of Caenorhabditis elegans","volume":"275","author":"Albertson D.","year":"1976","journal-title":"Phil. 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