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Cs<jats:sup>+<\/jats:sup> and ChTX, a polypeptide toxin from the venom of the scorpion <jats:italic>Leirus quinquestriatus<\/jats:italic>, are considered blockers of Ca<jats:sup>2+<\/jats:sup>\u2010activated K<jats:sup>+<\/jats:sup> channels in several somatic cells. Both agents inhibited the AR by 55\u201366%. The inhibition was completely reversed by the Na<jats:sup>+<\/jats:sup>\/K<jats:sup>+<\/jats:sup> ionophore nigericin, but not by the Ca<jats:sup>2+<\/jats:sup> ionophore A\u201023187. Results give evidence in support of a role for Ca<jats:sup>2+<\/jats:sup>\u2010activated K<jats:sup>+<\/jats:sup> channels in K<jats:sup>+<\/jats:sup> influx required for the occurrence of the hamster sperm acrosome reaction. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jez.1402690512","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T02:41:44Z","timestamp":1118457704000},"page":"484-488","source":"Crossref","is-referenced-by-count":8,"title":["Evidence in support of a role for Ca<sup>2+<\/sup>\u2010activated K<sup>+<\/sup> channels in the hamster sperm acrosome reaction"],"prefix":"10.1002","volume":"269","author":[{"given":"Miguel N.","family":"Llanos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.34.3.C1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod41.4.635"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1402320115"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(89)90164-4"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0690539"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.1120200409"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.10.3329"},{"key":"e_1_2_1_9_1","first-page":"51","article-title":"Phosphoinositides and their products in the mammalian sperm acrosome reaction","volume":"42","author":"Harrison R. 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