{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:33:00Z","timestamp":1760549580915},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T00:00:00Z","timestamp":1406678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Exp. Zool."],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label \/><jats:p>In this study, correlations between gonadal differentiation and gonadotrophic differentiation during early gonadal sex differentiation were examined in several strains from the Southern population of Japanese medaka, namely, Hd\u2010rR, d\u2010rR\/Tokyo, d\u2010rR\/Shizuoka, and NIESR. Gonadal sex differentiation showed a similar pattern in all strains, that is, a sex\u2010based difference in germ cell number was observed at hatching (XX\u2009&gt;\u2009XY). In addition, a transition of XX germ cells into meiosis was observed at hatching in all strains. However, the ratio of meiotic transition of XX germ cells differed among strains, indicating that Hd\u2010rR has fewer meiotic cells than other strains. Immunohistochemical analysis showed that glycoprotein \u03b1 subunit (Gpa) and follicle\u2010stimulating hormone \u03b2 subunit (Fshb), but not luteinizing hormone \u03b2 subunit (Lhb), localize to the pituitary at hatching in all strains examined. Although no sex differences were observed in the numbers of Gpa\u2010 and Fshb\u2010positive cells in the pituitary at hatching in Hd\u2010rR, d\u2010rR\/Tokyo, and NIESR strains, the d\u2010rR\/Shizuoka strain showed sex differences in the number of Fshb\u2010positive cells at hatching (XX\u2009&gt;\u2009XY); d\u2010rR\/Shizuoka is derived from d\u2010rR\/Tokyo. Even though d\u2010rR\/Shizuoka differs from its ancestral strain, d\u2010rR\/Tokyo, and Hd\u2010rR in Fshb expression pattern, this suggests that d\u2010rR\/Shizuoka shows potential for use as a model to study the molecular regulatory mechanisms of <jats:italic>fshb<\/jats:italic> subunit gene expression and Fsh cell differentiation in the pituitary. <jats:italic>J. Exp. Zool. 321A: 472\u2013477, 2014<\/jats:italic>. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jez.1879","type":"journal-article","created":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T15:42:31Z","timestamp":1406734951000},"page":"472-477","source":"Crossref","is-referenced-by-count":4,"title":["Relationships between gonadal and gonadotrophic differentiation during early gonadal sex differentiation in several strains from the Southern population of Japanese medaka (<i>Oryzias latipes<\/i>)"],"prefix":"10.1002","volume":"321","author":[{"given":"Yoshifumi","family":"Horie","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Reproductive Biology Graduate School of Integrated Pharmaceutical and Nutritional Sciences University of Shizuoka Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Reproductive Biology Institute for Environmental Sciences University of Shizuoka Shizuoka Japan"},{"name":"Laboratory of Molecular Reproductive Biology Graduate Division of Nutritional and Environmental Sciences University of Shizuoka Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,30]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2010.03.015"},{"key":"e_1_2_4_3_1","first-page":"289","article-title":"Oryzias sakaizumii, a new ricefish from northern Japan (Teleostei: Adrianichthyidae)","volume":"22","author":"Asai T","year":"2011","journal-title":"Ichthyol Explor Freshwaters"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-6480(03)00198-9"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00206337"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.21203"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.23860"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2011.12.047"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2014.04.036"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2004.03.012"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20158"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.21409"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.109.080986"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611707104"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2934"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh311"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0468"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-006-0086-0"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.07.039"},{"key":"e_1_2_4_20_1","first-page":"795","article-title":"Rigid isolation between the Northern population and the Southern population of the Medaka, Oryzias latipes","volume":"1","author":"Sakaizumi M.","year":"1984","journal-title":"Zool Sci"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.2307\/1444373"},{"key":"e_1_2_4_22_1","first-page":"385","article-title":"Sex differentiation of germ cells in the teleost, Oryzias latipes, during normal embryonic development","volume":"28","author":"Satoh N","year":"1972","journal-title":"J Embryol Exp Morphol"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2008.12.019"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2008.01.022"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.14.8.5592"},{"key":"e_1_2_4_26_1","first-page":"841","volume-title":"Advances in comparative endocrinology","author":"Swanson P","year":"1997"},{"key":"e_1_2_4_27_1","first-page":"419","article-title":"Seabream GnRH immunoreactivity in brain and pituitary of XX and XY Nile tilapia, Oreochromis niloticus during early development","volume":"309","author":"Swapna I","year":"2012","journal-title":"J Exp Zool A Ecol Genet Physiol"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.2108\/zsj.20.1279"},{"key":"e_1_2_4_29_1","doi-asserted-by":"publisher","DOI":"10.2108\/zsj.21.483"},{"key":"e_1_2_4_30_1","doi-asserted-by":"publisher","DOI":"10.2108\/zsj.21.977"},{"key":"e_1_2_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2008.10.013"},{"key":"e_1_2_4_32_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.112.101220"},{"key":"e_1_2_4_33_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.128.2.147"}],"container-title":["Journal of Experimental Zoology Part A: Ecological Genetics and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjez.1879","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jez.1879","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T18:52:39Z","timestamp":1696359159000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jez.1879"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,30]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1002\/jez.1879"],"URL":"https:\/\/doi.org\/10.1002\/jez.1879","archive":["Portico"],"relation":{},"ISSN":["1932-5223","1932-5231"],"issn-type":[{"value":"1932-5223","type":"print"},{"value":"1932-5231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,30]]}}}