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Exp. Zool."],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>The membrane progestin receptor \u03b1 (mPR\u03b1) plays an important role in the regulation of oocyte meiotic maturation in fish. However, the endocrine regulation of multiple spawning in fish with asynchronous ovarian development remains to be determined. We identified four genes (<jats:italic>FSH\u03b2<\/jats:italic>, <jats:italic>LH\u03b2<\/jats:italic>, <jats:italic>CG\u03b1<\/jats:italic> and <jats:italic>mPR\u03b1<\/jats:italic>) that are widely expressed in both the reproductive and non\u2010reproductive tissues of rock bream <jats:italic>Oplegnathus fasciatus<\/jats:italic> and examined their expression during ovarian maturation. The level of <jats:italic>FSH\u03b2<\/jats:italic> transcripts in the pituitary remained high during vitellogenic stages, when the plasma levels of estradiol\u201017\u03b2 reached maximum levels and oocyte development was stimulated. <jats:italic>LH\u03b2<\/jats:italic> expression in the pituitary and ovary reached maximum levels during oocyte maturation when the plasma levels of testosterone also reached a maximum. A significant correlation between <jats:italic>mPR\u03b1<\/jats:italic> transcript levels and the gonadosomatic index was observed during vitellogenesis and final maturation. Brain gonadotropin (<jats:italic>FSH\u03b2<\/jats:italic> and <jats:italic>LH\u03b2<\/jats:italic>) and <jats:italic>mPR\u03b1<\/jats:italic> were continuously expressed at different stages of ovarian development. The dynamic and diverse nature of gonadotropins and <jats:italic>mPR\u03b1<\/jats:italic> gene expression patterns suggests that these genes might jointly regulate ovarian development and maturation through the brain\u2013pituitary\u2013ovary axis in the rock bream endocrine system. <jats:italic>J. Exp. Zool. 323A: 430\u2013444, 2015<\/jats:italic>. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jez.1939","type":"journal-article","created":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T20:28:02Z","timestamp":1433363282000},"page":"430-444","source":"Crossref","is-referenced-by-count":3,"title":["Molecular and transcriptional characterization of <i>GTHs<\/i> and <i>mPR\u03b1<\/i> during ovarian maturation in rock bream <i>Oplegnathus fasciatus<\/i>"],"prefix":"10.1002","volume":"323","author":[{"given":"Bao","family":"Shi","sequence":"first","affiliation":[{"name":"Qingdao Key Laboratory for Marine Fish Breeding and Biotechnology Key Laboratory for the Sustainable Development of Marine Fisheries, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences Qingdao Shandong P.R. 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