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Most studies suggest a positive involvement of thyroid hormones with some aspects of reproduction, but some studies support a negative role for thyroid hormones at certain life stages. Comprehensive studies of gene activation\/suppression by thyroid hormones and their absence at various levels of the hypothalamo\u2013pituitary\u2013gonadal axis coupled with observations of adrenocorticoid activity, reproductive performance, and metabolic involvement are needed to understand this complex relationship.<\/jats:p>","DOI":"10.1002\/jez.2737","type":"journal-article","created":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T11:28:50Z","timestamp":1690802930000},"page":"869-877","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Thyroid and reproduction in amphibians and reptiles"],"prefix":"10.1002","volume":"339","author":[{"given":"David O.","family":"Norris","sequence":"first","affiliation":[{"name":"Department of Integrative Physiology University of Colorado Boulder Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.46.1183.216"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1400240303"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-016-7631-z"},{"key":"e_1_2_8_5_1","first-page":"215","volume-title":"Hormones and reproduction of vertebrates: Mammals","author":"Bales K.","year":"2011"},{"key":"e_1_2_8_6_1","first-page":"277","volume-title":"Hormones and reproduction of vertebrates: Reptiles","author":"Blanvillain G.","year":"2011"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/es1025195"},{"key":"e_1_2_8_8_1","first-page":"373","volume-title":"Hormones and reproduction of vertebrates: Reptiles","author":"Boggs A. 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