{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:57:13Z","timestamp":1779919033229,"version":"3.53.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,9,10]],"date-time":"2003-09-10T00:00:00Z","timestamp":1063152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Exp. Zool."],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Metabolic responses of cholecalciferol (VD<jats:sub>3<\/jats:sub>) and minerals (Ca, P and Mg) in abalone <jats:italic>Haliotis discus hannai<\/jats:italic> Ino to dietary VD<jats:sub>3<\/jats:sub> and phosphorus (P) were investigated. Based on a 2 \u00d7 2 factorial design, four casein\u2010gelatin\u2010based diets were formulated. The basal diet was supplemented with either 0 or 2000 IU VD<jats:sub>3<\/jats:sub>\/kg diet and 0 or 10 g P\/kg diet. The abalone was reared in P\u2010free artificial seawater for 55 days. Results showed that dietary VD<jats:sub>3<\/jats:sub> was hydroxylated to 25\u2010hydroxyvitamin D<jats:sub>3<\/jats:sub> [25(OH)D<jats:sub>3<\/jats:sub>] and 1\u03b1,25\u2010dihydroxyvitamin D<jats:sub>3<\/jats:sub> [1\u03b1,25(OH)<jats:sub>2<\/jats:sub>D<jats:sub>3<\/jats:sub>] in abalone, and subsequently raised the serum levels of these two VD<jats:sub>3<\/jats:sub> metabolites. Dietary P deficiency elevated serum 1\u03b1,25(OH)<jats:sub>2<\/jats:sub>D<jats:sub>3<\/jats:sub> level only when the dietary VD<jats:sub>3<\/jats:sub> supplementation was sufficient. The supplementations of either dietary VD<jats:sub>3<\/jats:sub> or P significantly increased the levels of P in serum, mantle and hepatopancreas, and only the addition of VD<jats:sub>3<\/jats:sub> significantly raised the concentrations of Ca in serum and mantle (<jats:italic>P<\/jats:italic>&lt;0.05). Interaction between dietary VD<jats:sub>3<\/jats:sub> and P was only found significant on the concentrations of P and Mg in mantle (<jats:italic>P<\/jats:italic>&lt;0.05). The concentrations of Ca, P and Mg in muscle were not significantly influenced by these dietary treatments. Hence, the metabolic responses in serum, muscle, mantle and hepatopancreas of abalone to dietary VD<jats:sub>3<\/jats:sub> and P were in different manners. <jats:italic>J. Exp. Zool. 299A:110\u2013117, 2003<\/jats:italic>. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jez.a.10295","type":"journal-article","created":{"date-parts":[[2003,9,11]],"date-time":"2003-09-11T13:24:02Z","timestamp":1063286642000},"page":"110-117","source":"Crossref","is-referenced-by-count":22,"title":["Metabolic responses to dietary cholecalciferol and phosphorus in abalone <i>Haliotis discus hannai<\/i> ino"],"prefix":"10.1002","volume":"299A","author":[{"given":"Wenbing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangsen","family":"mai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongming","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,9,10]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1016\/S0021-9258(17)33513-5","article-title":"Stimulation of 25\u2010hydroxyvitamin D3\u2010l\u03b1\u2010hydroxylase by phosphate depletion","volume":"251","author":"Baxter LA","year":"1976","journal-title":"J Biol Chem"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1016\/S0021-9258(19)43995-1","article-title":"The regulation of the rat liver calciferol\u201025\u2010hydroxylase","volume":"248","author":"Bhattacharyya MH","year":"1973","journal-title":"J Biol Chem"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-9629(92)90265-R"},{"key":"e_1_2_1_5_1","first-page":"87","volume-title":"Vitamin D","author":"Cooke NC","year":"1997"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1095-6433(00)00289-0"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.202.23.3285"},{"key":"e_1_2_1_8_1","first-page":"7","article-title":"Recent advances in our understanding of the vitamin D endocrine system","volume":"37","author":"DeLuca HF","year":"1976","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00335537"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/121.1.13"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nu.04.070184.002425"},{"key":"e_1_2_1_12_1","first-page":"587","volume-title":"Vitamin D","author":"Hollis BW","year":"1997"},{"key":"e_1_2_1_13_1","first-page":"65","article-title":"Calcitriol metabolism during chronic metabolic acidosis","volume":"9","author":"Langman CB","year":"1989","journal-title":"Semin Nephrol"},{"key":"e_1_2_1_14_1","first-page":"165","article-title":"Comparative studies on the nutrition of two species of abalone, Haliotis tuberculata L. and H. discus hannai Ino. 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