{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:19:54Z","timestamp":1777558794808,"version":"3.51.4"},"reference-count":73,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,5]],"date-time":"2023-06-05T00:00:00Z","timestamp":1685923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Exp Zool Pt B"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Serially homologous structures may have complex patterns of regionalization and morphological integration, influenced by developmental\n                    <jats:italic>Hox<\/jats:italic>\n                    gene expression and functional constraints. The vertebral column, consisting of a number of repeated, developmentally constrained, and highly integrated units\u2014vertebrae\u2014is such a complex serially homologous structure. Functional diversification increases regionalization and modularity of the vertebral column, particularly in mammals. For salamanders, three concepts of regionalization of the vertebral column have been proposed, recognizing one, two, or three presacral regions. Using three\u2010dimensional geometric morphometrics on vertebra models acquired with microcomputerized tomography scanning,\u00a0we explored the covariation of vertebrae in four closely related taxa of small\u2010bodied newts in the genus\n                    <jats:italic>Lissotriton<\/jats:italic>\n                    . The data were analyzed by segmented linear regression to explore patterns of vertebral regionalization and by a two\u2010block partial least squares method to test for morphological integration. All taxa show a morphological shift posterior to the fifth trunk vertebra, which corresponds to the two\u2010region concept. However, morphological integration is found to be strongest in the mid\u2010trunk. Taken jointly, these results indicate a highly integrated presacral vertebral column with a subtle two\u2010region differentiation. The results are discussed in relation to specific functional requirements, developmental and phylogenetic constraints, and specific requirements posed by a biphasic life cycle and different locomotor modes (swimming vs. walking). Further research should be conducted on different ontogenetic stages and closely related but ecologically differentiated species.\n                  <\/jats:p>","DOI":"10.1002\/jez.b.23205","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T14:35:44Z","timestamp":1686148544000},"page":"403-413","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Regionalization and morphological integration in the vertebral column of Eurasian small\u2010bodied newts (Salamandridae:\n                    <i>Lissotriton<\/i>\n                    )"],"prefix":"10.1002","volume":"340","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1158-5537","authenticated-orcid":false,"given":"Aleksandar","family":"Uro\u0161evi\u0107","sequence":"first","affiliation":[{"name":"Department of Evolutionary Biology, Institute for Biological Research \u201dSini\u0161a Stankovi\u0107,\u201d National Institute of the Republic of Serbia University of Belgrade Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9115-6622","authenticated-orcid":false,"given":"Maja","family":"Ajdukovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Evolutionary Biology, Institute for Biological Research \u201dSini\u0161a Stankovi\u0107,\u201d National Institute of the Republic of Serbia University of Belgrade Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8850-5251","authenticated-orcid":false,"given":"Tijana","family":"Vu\u010di\u0107","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Faculty of Biology University of Belgrade  Belgrade Serbia"},{"name":"Animal Sciences, Institute of Biology Leiden University  Leiden The Netherlands"},{"name":"Naturalis Biodiversity Center  Leiden The Netherland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9320-4296","authenticated-orcid":false,"given":"Stefan J.","family":"Scholtes","sequence":"additional","affiliation":[{"name":"Naturalis Biodiversity Center  Leiden The Netherland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3229-5993","authenticated-orcid":false,"given":"Jan W.","family":"Arntzen","sequence":"additional","affiliation":[{"name":"Animal Sciences, Institute of Biology Leiden University  Leiden The Netherlands"},{"name":"Naturalis Biodiversity Center  Leiden The Netherland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6247-8849","authenticated-orcid":false,"given":"Ana","family":"Ivanovi\u0107","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Faculty of Biology University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/2041-210X.12511"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/evo.13045"},{"key":"e_1_2_10_4_1","unstructured":"Adams D. 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