{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T17:29:23Z","timestamp":1771262963867,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T00:00:00Z","timestamp":1716681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Foot and Ankle Research"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background &amp; Aims<\/jats:title><jats:p>Surgery plays a key role in the management of complicated diabetic foot disease (DFD). Currently, indications for medical versus surgical management are poorly defined. Prompt identification of patients who require surgery may reduce morbidities and length of hospital stay. This study aims to analyse factors in DFD that necessitate early surgical interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients admitted under a multi\u2010disciplinary diabetic foot team in a tertiary institution over 2\u00a0years were included in a retrospective case\u2010control study comparing patients who received medical management and patients who received surgical management. Logistic regression was performed to identify factors associated with surgical management of diabetic foot complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred and forty patients were included. 49% of patients required surgical management. Toe ulceration, elevated C\u2010reactive protein (CRP), and the presence of osteomyelitis were associated with surgical management. Multivariate analysis calculated an odds ratio (OR) of 1.01 for CRP (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), OR 2.19 (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.019) favouring surgical management for forefoot ulcers, and OR 2.2 (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.019) if osteomyelitis was present.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with elevated CRP levels, a forefoot diabetic ulcer and established osteomyelitis were more likely to undergo surgical management. Prompt recognition of these patients has the potential benefit of earlier decision making in definitive surgical interventions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jfa2.12024","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T04:19:56Z","timestamp":1716783596000},"source":"Crossref","is-referenced-by-count":2,"title":["Predictors of operative management in diabetic foot ulcers"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6270-0411","authenticated-orcid":false,"given":"Amos","family":"Au","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery Monash Health  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erwin","family":"Yii","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Eastern Health  Box Hill Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Andric","sequence":"additional","affiliation":[{"name":"Department of Podiatry Monash Health  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Monash Health  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Saunder","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Monash Health  Clayton Victoria Australia"},{"name":"Department of Surgery School of Clinical Sciences at Monash Health Monash University  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Yii","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Monash Health  Clayton Victoria Australia"},{"name":"Department of Surgery School of Clinical Sciences at Monash Health Monash University  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,26]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Australian Diabetes\u2010Related Foot Disease Strategy 2018\u20102022: The First Step towards Ending Avoidable Amputations within a Generation","author":"Van Netten J. J.","year":"2017"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124446"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12404"},{"key":"e_1_2_12_5_1","volume-title":"Diabetes: Australian Facts 2008. Diabetes Series No. 8. Cat. No. CVD 40","author":"Australian Institute of Health and Welfare","year":"2008"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.2.286"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2018.1417037"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/dmso.s181198"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surge.2020.01.007"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpm.2007.04.001"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000164172.28918.3f"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734615596892"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2013.06.010"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc13\u20101526"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2017.01207"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-014-0630-5"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.10.1799"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2867"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.08.003"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.54522\/jvsgbi.2022.020"},{"key":"e_1_2_12_21_1","volume-title":"Australian Burden of Disease Study: Impact and Causes of Illness and Death in Aboriginal and Torres Strait Islander People 2011","author":"Australian Institute of Health and Welfare (AIHW)","year":"2016"}],"container-title":["Journal of Foot and Ankle Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jfa2.12024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T06:12:25Z","timestamp":1719209545000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jfa2.12024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,26]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/jfa2.12024"],"URL":"https:\/\/doi.org\/10.1002\/jfa2.12024","archive":["Portico"],"relation":{},"ISSN":["1757-1146","1757-1146"],"issn-type":[{"value":"1757-1146","type":"print"},{"value":"1757-1146","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,26]]},"article-number":"e12024"}}