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Concurrent automated toe, thumb and brachial systolic blood pressures as well as comfort ratings for these measures (using a 10\u00a0mm visual analogue scale) were captured once by a research assistant. Automated thumb and brachial measures showed fair correlation (<jats:italic>\u03c1<\/jats:italic>\u00a0=\u00a00.36, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.03) and a toe\u2013thumb index and toe\u2013brachial index good correlation (<jats:italic>\u03c1<\/jats:italic>\u00a0=\u00a00.62, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). Intraclass correlation coefficients (ICC) identified moderate intra\u2010rater reliability for manual thumb pressures for Rater 1 and 2 (ICC 0.57, 95% CI [0.14, 0.79] and ICC 0.74, 95% CI [0.49, 0.87], respectively), while inter\u2010rater reliability was poor (ICC\u00a0=\u00a00.16, 95% CI [\u22120.85, 0.47]). Concurrent validity comparing manual and automated measures for thumb pressure was also poor (ICC \u22120.05, 95% CI [\u22121.06, 0.72] and ICC 0.42, 95% CI [\u22120.16, 0.72] Rater 1 and 2 respectively). Thumb measures were significantly more comfortable than brachial measures (5\u00a0mm, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.00).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Thumb systolic pressures are correlated with brachial systolic pressures, with reasonable intra\u2010rater reliability, however, correlation is only fair and measurement error wider than clinically acceptable. Furthermore, manual measures are poorly correlated with automated units. Consequently, caution is required in applying these techniques. As thumb measures were perceived as significantly more comfortable than brachial measures and have an advantage where brachial pressures cannot, or should not, be obtained, further evaluation is warranted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jfa2.70011","type":"journal-article","created":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T15:10:12Z","timestamp":1729350612000},"source":"Crossref","is-referenced-by-count":1,"title":["The use of a novel toe\u2013thumb pressure index for assessing arterial status in the lower limb. A reliability and validity study"],"prefix":"10.1002","volume":"17","author":[{"given":"Juliana","family":"Mazzeo","sequence":"first","affiliation":[{"name":"Allied Health and Human Performance Innovation, Implementation and Clinical Translation in Health (IIMPACT) University of South Australia  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5730-1611","authenticated-orcid":false,"given":"Helen A.","family":"Banwell","sequence":"additional","affiliation":[{"name":"Allied Health and Human Performance Innovation, Implementation and Clinical Translation in Health (IIMPACT) University of South Australia  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0014-3023","authenticated-orcid":false,"given":"Peta E.","family":"Tehan","sequence":"additional","affiliation":[{"name":"School of Clinical and Molecular Sciences, Faculty of 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