{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:56:49Z","timestamp":1753869409407,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Foot and Ankle Research"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Diabetic wet gangrene of the toes is a serious condition that puts at risk the limb and life of patients. Two types of amputation are used when infection is around the metatarsophalangeal joint (MTPJ): complete toe disarticulation and toe amputation including metatarsal head resection. Because very few published papers analyzed the results of toe amputation for wet gangrene, our study aimed to evaluate the outcomes of both techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective comparative study of highly selective patients admitted for a single toe\/ray diabetic wet gangrene that were treated with toe amputation through MTPJ (TA\u2010MTPJ) versus toe amputation with resection of the metatarsal head (TA\u2010MHR). Three primary outcomes were set for analysis: healing rate and the frequencies of infection recurrence and additional surgeries, including reamputations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sample included 31 cases: 12 cases (39%) with TA\u2010MTPJ and 19 cases (61%) with TA\u2010MHR. Outcomes of TA\u2010MTPJ versus TA\u2010MHR were as follows: (a) healing frequency 66.7% versus 58% (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.6), (b) infection recurrence 50% versus 52.6% (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.8), (c) osteomyelitis 41.6% versus 42.1% (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.8), and (d) reamputation 33.3% versus 47.3% (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.4).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study showed high complications after toe amputation for diabetic digital wet gangrene, with a trend for higher frequency of complications after TA\u2010MHR compared to TA\u2010MTPJ. For any type of amputation required for toe wet gangrene, it is likely that a more proximal level of index amputation is required.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jfa2.70052","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T09:55:58Z","timestamp":1747734958000},"source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Diabetic Toe Amputation With Versus Without Metatarsal Head Resection for Single Ray Wet Gangrene: A Preliminary Study"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0094-9892","authenticated-orcid":false,"given":"Kaissar","family":"Yammine","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Lebanese American University Medical Center\u2010Rizk Hospital School of Medicine Lebanese American University  Beirut Lebanon"},{"name":"Diabetic Foot Clinic Lebanese American University Medical Center\u2010Rizk Hospital  Beirut Lebanon"},{"name":"Center for Evidence\u2010Based Anatomy, Sport &amp; Orthopedics Research  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Honeine","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Lebanese American University Medical Center\u2010Rizk Hospital School of Medicine Lebanese American University  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Mouawad","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Lebanese American University Medical Center\u2010Rizk Hospital School of Medicine Lebanese American University  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghadi Abou","family":"Orm","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Lebanese American University Medical Center\u2010Rizk Hospital School of Medicine Lebanese American University  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youssef","family":"Jamaleddine","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Lebanese American University Medical Center\u2010Rizk Hospital School of Medicine Lebanese American University  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chahine","family":"Assi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Lebanese American University Medical Center\u2010Rizk Hospital School of Medicine Lebanese American University  Beirut Lebanon"},{"name":"Center for Evidence\u2010Based Anatomy, Sport &amp; Orthopedics Research  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12404"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2021.655902"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.2002.00740.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0239236"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010008\u20101131\u20108"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jfas.2020.04.025"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.2.217"},{"issue":"3","key":"e_1_2_11_9_1","first-page":"20","article-title":"Location of Lower\u2010Extremity Diabetic Foot Ulcers With Concomitant Arterial or Venous Disease","volume":"11","author":"Ellis S.","year":"2020","journal-title":"Wounds International"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1938640019857795"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/19386400231201516"},{"key":"e_1_2_11_12_1","unstructured":"Available on 16\/08\/2023 https:\/\/jbi.global\/critical\u2010appraisal\u2010tools."},{"issue":"1","key":"e_1_2_11_13_1","first-page":"19","volume":"25","author":"Tenze L.","year":"2001","journal-title":"Medicina E Chirurgia Della Caviglia E Del Piede"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0741\u20105214(99)70078\u20109"}],"container-title":["Journal of Foot and Ankle Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jfa2.70052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T15:04:11Z","timestamp":1750863851000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jfa2.70052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,19]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/jfa2.70052"],"URL":"https:\/\/doi.org\/10.1002\/jfa2.70052","archive":["Portico"],"relation":{},"ISSN":["1757-1146","1757-1146"],"issn-type":[{"type":"print","value":"1757-1146"},{"type":"electronic","value":"1757-1146"}],"subject":[],"published":{"date-parts":[[2025,5,19]]},"article-number":"e70052"}}