{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T17:16:18Z","timestamp":1788369378778,"version":"build-2803163510"},"reference-count":60,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Foot and Ankle Research"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The aim of this study was to systematically review the risk of falls in people with diabetes\u2010related foot ulcers (DFU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search of Medline, Pubmed, Embase, Cochrane and CINAHL was undertaken to identify observational studies reporting falls and containing a group of people with a DFU and a control group with diabetes but no DFU. Risk of bias was assessed by a modified Newcastle\u2013Ottawa Scale. Meta\u2010analysis was performed using a random effects model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Four studies involving 3643 participants with a DFU and 42,436 participants with diabetes but no DFU were included. A meta\u2010analysis showed high heterogeneity between studies (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a095%) and an increased risk of falls in people with DFU (risk ratio 2.25 and 95% CI 1.05\u20134.84). One study had a low risk of bias and three studies had a high risk of bias. Leave\u2010one\u2010out analyses showed that exclusion of the study with the largest effect on heterogeneity resulted in a risk ratio of 1.80 (95% CI 1.33\u20132.43 and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a00%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Currently available evidence suggests people with a DFU have a higher risk of falls but most past studies have a high risk of bias. Further well\u2010designed cohort studies are required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jfa2.70057","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T01:15:23Z","timestamp":1750122923000},"source":"Crossref","is-referenced-by-count":5,"title":["A Systematic Review Examining the Association of Falls With Diabetes\u2010Related Foot Ulcers"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7544-5861","authenticated-orcid":false,"given":"Mike","family":"Wu","sequence":"first","affiliation":[{"name":"Queensland Research Centre for Peripheral Vascular Disease College of Medicine and Dentistry James Cook University  Townsville Australia"},{"name":"The Department of Vascular and Endovascular Surgery Townsville University Hospital  Townsville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallika","family":"Sinha","sequence":"additional","affiliation":[{"name":"College 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