{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T07:22:47Z","timestamp":1774596167370,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Foot and Ankle Research"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with rheumatoid arthritis (RA) may continue to experience foot\u2010related disability despite clinical remission. Foot involvement is associated with self\u2010reported disability and objective gait alterations. Foot involvement is heterogeneous; studying patients with localised forefoot pain may help clarify which structural and inflammatory factors are associated with functional impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To identify clinical, structural and imaging factors associated with disability and gait performance in patients with RA in clinical remission with metatarsal\u2010region forefoot pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cross\u2010sectional study of 81 patients with RA in remission with metatarsal\u2010region forefoot pain. Outcomes were Foot Function Index disability and activity limitation (FFI\u2010D and FFI\u2010AL), gait velocity (GV) and double\u2010support time (DS). Associations were examined using Spearman correlations, age\u2010 and BMI\u2010adjusted individual linear regression, parsimonious multivariable linear regression and exploratory cluster analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean (SD) FFI\u2010D and FFI\u2010AL were 29.8 (29.4) and 29.1 (27.7); gait velocity (GV) was 0.90 (0.34) m\/s and double\u2010support time (DS) was 22.9 (8.2)% of the gait cycle. In bivariate and age\/BMI\u2010adjusted analyses, graded structural measures showed more consistent associations with disability and gait outcomes than dichotomous\/count variables. In parsimonious models, disability (FFI\u2010D\/FFI\u2010AL) was independently associated with pain intensity (VAS) and first metatarsophalangeal joint stiffness\/limited dorsiflexion (1stMTP), whereas gait performance was mainly associated with age\/BMI, greater graded forefoot structural severity and 1stMTP. Cluster analysis identified a higher grey\u2010scale synovitis (GS)\/lower structural\u2010burden group and a lower GS\/higher structural\u2010burden group, with worse function and slower gait in the latter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In RA remission with metatarsal\u2010region forefoot pain, perceived disability is mainly associated with pain and forefoot stiffness, whereas gait performance is more closely related to age\/BMI and graded forefoot structural severity. These findings support severity\u2010based region\u2010specific structural assessment alongside pain evaluation in clinical follow\u2010up, to avoid underestimating the independent contribution of structural damage to function and gait.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jfa2.70133","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T05:50:20Z","timestamp":1770961820000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical and Structural Associations of Disability and Gait Performance in Patients With Rheumatoid Arthritis in Remission and Metatarsal Pain"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1052-5837","authenticated-orcid":false,"given":"Rebeca","family":"Bueno Fermoso","sequence":"first","affiliation":[{"name":"Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7257-3949","authenticated-orcid":false,"given":"Rosario","family":"Morales Lozano","sequence":"additional","affiliation":[{"name":"Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Mart\u00ednez Rinc\u00f3n","sequence":"additional","affiliation":[{"name":"Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6604-9136","authenticated-orcid":false,"given":"Pablo","family":"Garc\u00eda Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2800-7487","authenticated-orcid":false,"given":"Juan Miguel","family":"L\u00f3pez Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Villalba  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3026-531X","authenticated-orcid":false,"given":"Maria Luz","family":"Gonz\u00e1lez Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,12]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110079401501106"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010009\u20101312\u2010y"},{"issue":"3","key":"e_1_2_14_4_1","first-page":"480","article-title":"To What Extent Is Foot Pain Related to Biomechanical Changes and Ultrasound\u2010Detected Abnormalities in Rheumatoid Arthritis?","volume":"34","author":"Gonz\u00e1lez\u2010Fern\u00e1ndez M. 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