{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:58:08Z","timestamp":1791266288397,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Foot and Ankle Research"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lateral wedge insoles (LWIs) are a non\u2010surgical adjunct treatment for knee osteoarthritis (OA) that has been shown to reduce the knee adduction moment\u2014a biomechanical risk factor for knee OA disease progression. Though worn in one's shoes, little is known of the effects of LWIs use on the foot or ankle. Importantly, it unknown whether their use enhances foot symptoms in people with knee OA and concomitant foot pain, thus questioning the general appropriateness of their use in this subgroup.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a pilot, feasibility randomized controlled trial to assess study approaches and general effects of LWIs use in people with knee OA and foot pain. 30 individuals with foot pain and radiographically\u2010confirmed knee OA were randomized to a 12\u2010week intervention using either standalone 6\u2010degree LWIs or LWIs integrated with custom foot and arch support. Feasibility outcomes included: recruitment and retention outcomes; insoles usage, reporting, and comfort; and adverse events. We also examined foot (Foot Function Index pain and difficulty subscales) and knee symptoms (Knee Osteoarthritis Outcomes Severity Score pain and daily function subscales), and gait biomechanics (knee adduction and flexion moment peaks and impulses, ankle\/subtalar eversion peaks) before and after the 12\u2010week intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All feasibility criteria were met, and no major adverse events were reported. Participants found the insoles moderately comfortable (7\/10), and most weeks (278\/336, 83%) met the acceptable 30\u00a0min per day wear time threshold. Though no statistical comparisons were made, changes in clinical and biomechanical outcomes were consistent with previous research; specifically, trends toward improvement in knee pain and function, as well as knee adduction moment magnitudes, in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Lateral wedge insoles, with or without support, appear safe for people with knee OA and concomitant foot pain. Given positive feasibility and efficacy observations, future research in this area is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jfa2.70171","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:45:37Z","timestamp":1784004337000},"source":"Crossref","is-referenced-by-count":0,"title":["Lateral Wedge Insoles With and Without Contoured Arch Support for People With Knee Osteoarthritis and Foot Pain: A Pilot, Feasibility Randomized Controlled Trial"],"prefix":"10.1002","volume":"19","author":[{"given":"Michael A.","family":"Hunt","sequence":"first","affiliation":[{"name":"Motion Analysis and Biofeedback Laboratory University of British Columbia  Vancouver British Columbia Canada"},{"name":"Department of Physical Therapy University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha M.","family":"Krowchuk","sequence":"additional","affiliation":[{"name":"Motion Analysis and Biofeedback Laboratory University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haocheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Motion Analysis and Biofeedback Laboratory University of British Columbia  Vancouver British Columbia Canada"},{"name":"Graduate Programs in Rehabilitation Sciences University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Kintec Footlabs  Surrey British Columbia Canada"},{"name":"School of Mechatronics Systems Engineering Simon Fraser University  Burnaby British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor B.","family":"Birmingham","sequence":"additional","affiliation":[{"name":"School of Physical Therapy University of Western Ontario  London Ontario Canada"},{"name":"Wolf Orthopedic Biomechanics Laboratory Fowler Kennedy Sport Medicine Clinic  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse M.","family":"Charlton","sequence":"additional","affiliation":[{"name":"School of Kinesiology University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2665\u20109913(23)00163\u20107"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24035"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22933"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.7.617"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.147082"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22564"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2021.10.010"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2017.08.017"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2018.05.014"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102016\u2010097108"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22797"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23326"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22666"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.243229"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8654107"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40808"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22537"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20431"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2016.12.003"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5239"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100070611"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.4.494"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110070602700707"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757\u20101146\u20106\u20105"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891\u2010022\u201005374\u2010x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107525\u20101\u201064"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2016.03.010"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22247"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2018.04.011"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2025.106740"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40814\u2010019\u20100469\u20107"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13047\u2010017\u20100201\u2010x"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.23174"}],"container-title":["Journal of Foot and Ankle Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jfa2.70171","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jfa2.70171","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jfa2.70171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:49:18Z","timestamp":1791265758000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jfa2.70171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/jfa2.70171"],"URL":"https:\/\/doi.org\/10.1002\/jfa2.70171","archive":["Portico"],"relation":{},"ISSN":["1757-1146","1757-1146"],"issn-type":[{"value":"1757-1146","type":"print"},{"value":"1757-1146","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,13]]},"article-number":"e70171"}}