{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:41:52Z","timestamp":1791384112292,"version":"4.3.3"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T00:00:00Z","timestamp":1563235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003579","name":"University of Toronto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003579","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Consanguinity, the union between two individuals who are related as second cousins or closer, is a long\u2010standing and respected tradition in many communities. Although there are social and economic benefits of consanguineous unions, offspring are at increased risk of having an inherited genetic condition or congenital anomaly. Genetic counseling services for consanguinity are available to couples at many centers. However, little is known about patient expectations of and experiences with genetic counseling for this indication, or their perspectives on genetic screening relevant to family planning, such as expanded carrier screening (ECS). This exploratory qualitative study involved interviews with 13 individuals who had recently received preconception or prenatal genetic counseling for consanguinity at a single center. We sought to gain insight into their expectations for the genetic counseling session, experiences discussing family history and reproductive risks with the genetic counselor, and views on ECS. Interview transcripts were analyzed using an interpretive descriptive approach. Data analysis revealed three main themes: (a) anticipation balances apprehension before the appointment; (b) genetic counseling reduces anxiety and empowers; and (c) the need for wider information dissemination about consanguinity\u2010related risks and genetic services. Our findings support the personal utility of genetic counseling for consanguinity and demonstrate the need for increased visibility and access to genetics information, counseling, and testing relevant to this patient population.<\/jats:p>","DOI":"10.1002\/jgc4.1150","type":"journal-article","created":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T05:29:27Z","timestamp":1563341367000},"page":"982-992","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prenatal and preconception genetic counseling for consanguinity: Consanguineous couples' expectations, experiences, and perspectives"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8347-9998","authenticated-orcid":false,"given":"Emily","family":"Thain","sequence":"first","affiliation":[{"name":"Department of Molecular Genetics University of Toronto Toronto ON Canada"},{"name":"Division of Clinical and Metabolic Genetics, Department of Pediatrics The Hospital for Sick Children Toronto ON Canada"},{"name":"Department of Genetic Counselling The Hospital for Sick Children Toronto ON Canada"},{"name":"Familial Cancer Clinic Princess Margaret Cancer Centre Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Shuman","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics University of Toronto Toronto ON Canada"},{"name":"Division of Clinical and Metabolic Genetics, Department of Pediatrics The Hospital for Sick Children Toronto ON Canada"},{"name":"Department of Genetic Counselling The Hospital for Sick Children Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics University of Toronto Toronto ON Canada"},{"name":"Genetics Program North York General Hospital Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Sappleton","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children Centre for Innovation and Excellence in Child and Family\u2010Centred Care Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Myles\u2010Reid","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics University of Toronto Toronto ON Canada"},{"name":"Prenatal Diagnosis and Medical Genetics Program, Department of Obstetrics and Gynecology Mount Sinai Hospital Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Chitayat","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics University of Toronto Toronto ON Canada"},{"name":"Division of Clinical and Metabolic Genetics, Department of Pediatrics The Hospital for Sick Children Toronto ON Canada"},{"name":"Prenatal Diagnosis and Medical Genetics Program, Department of Obstetrics and Gynecology Mount Sinai Hospital Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Gibbons","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics University of Toronto Toronto ON Canada"},{"name":"Genetics Program North York General Hospital Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1391"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1014593404915"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2307\/2137601"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0004.2001.600201.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.08.003"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","unstructured":"Committee Opinion No. 690. 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